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S6-haploinsufficiency activates the p53 tumor suppressor.
Panić L, Montagne J, Cokarić M, Volarević S. Panić L, et al. Among authors: volarevic s. Cell Cycle. 2007 Jan 1;6(1):20-4. doi: 10.4161/cc.6.1.3666. Epub 2007 Jan 29. Cell Cycle. 2007. PMID: 17245121 Review.
Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress.
Bursać S, Brdovčak MC, Pfannkuchen M, Orsolić I, Golomb L, Zhu Y, Katz C, Daftuar L, Grabušić K, Vukelić I, Filić V, Oren M, Prives C, Volarevic S. Bursać S, et al. Among authors: volarevic s. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20467-72. doi: 10.1073/pnas.1218535109. Epub 2012 Nov 20. Proc Natl Acad Sci U S A. 2012. PMID: 23169665 Free PMC article.
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