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Multiplex secretome engineering enhances recombinant protein production and purity.
Kol S, Ley D, Wulff T, Decker M, Arnsdorf J, Schoffelen S, Hansen AH, Jensen TL, Gutierrez JM, Chiang AWT, Masson HO, Palsson BO, Voldborg BG, Pedersen LE, Kildegaard HF, Lee GM, Lewis NE. Kol S, et al. Among authors: voldborg bg. Nat Commun. 2020 Apr 20;11(1):1908. doi: 10.1038/s41467-020-15866-w. Nat Commun. 2020. PMID: 32313013 Free PMC article.
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE. Hefzi H, et al. Among authors: voldborg bg. Cell Syst. 2016 Nov 23;3(5):434-443.e8. doi: 10.1016/j.cels.2016.10.020. Cell Syst. 2016. PMID: 27883890 Free PMC article.
Combating viral contaminants in CHO cells by engineering innate immunity.
Chiang AWT, Li S, Kellman BP, Chattopadhyay G, Zhang Y, Kuo CC, Gutierrez JM, Ghazi F, Schmeisser H, Ménard P, Bjørn SP, Voldborg BG, Rosenberg AS, Puig M, Lewis NE. Chiang AWT, et al. Among authors: voldborg bg. Sci Rep. 2019 Jun 20;9(1):8827. doi: 10.1038/s41598-019-45126-x. Sci Rep. 2019. PMID: 31222165 Free PMC article.
High throughput generation of a resource of the human secretome in mammalian cells.
Tegel H, Dannemeyer M, Kanje S, Sivertsson Å, Berling A, Svensson AS, Hober A, Enstedt H, Volk AL, Lundqvist M, Moradi M, Afshari D, Ekblad S, Xu L, Westin M, Bidad F, Schiavone LH, Davies R, Mayr LM, Knight S, Göpel SO, Voldborg BG, Edfors F, Forsström B, von Feilitzen K, Zwahlen M, Rockberg J, Takanen JO, Uhlén M, Hober S. Tegel H, et al. Among authors: voldborg bg. N Biotechnol. 2020 Sep 25;58:45-54. doi: 10.1016/j.nbt.2020.05.002. Epub 2020 Jun 2. N Biotechnol. 2020. PMID: 32502629 Free article.
30 results