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Page 1
Malaria Genomics in the Era of Eradication.
Neafsey DE, Volkman SK. Neafsey DE, et al. Cold Spring Harb Perspect Med. 2017 Aug 1;7(8):a025544. doi: 10.1101/cshperspect.a025544. Cold Spring Harb Perspect Med. 2017. PMID: 28389516 Free PMC article. Review.
The first reference genome assembly for the Plasmodium falciparum malaria parasite was completed over a decade ago, and the impact of this and other genomic resources on malaria research has been significant. ...Specifically, we focus on how population genomic strat …
The first reference genome assembly for the Plasmodium falciparum malaria parasite was completed over a decade ago, and the impact of …
Harnessing genomics and genome biology to understand malaria biology.
Volkman SK, Neafsey DE, Schaffner SF, Park DJ, Wirth DF. Volkman SK, et al. Nat Rev Genet. 2012 Apr 12;13(5):315-28. doi: 10.1038/nrg3187. Nat Rev Genet. 2012. PMID: 22495435 Review.
Malaria is an important human disease and is the target of a global eradication campaign. New technological and informatics advancements in population genomics are being leveraged to identify genetic loci under selection in the malaria parasite and to find variants
Malaria is an important human disease and is the target of a global eradication campaign. New technological and informatics advanceme
Genomic investigation of atypical malaria cases in Kanel, northern Senegal.
Sy M, Badiane AS, Deme AB, Gaye A, Ndiaye T, Fall FB, Siddle KJ, Dieye B, Ndiaye YD, Diallo MA, Diongue K, Seck MC, Ndiaye IM, Cissé M, Gueye AB, Sène D, Dieye Y, Souané T, MacInnis B, Volkman SK, Wirth DF, Ndiaye D. Sy M, et al. Malar J. 2021 Feb 19;20(1):103. doi: 10.1186/s12936-021-03637-x. Malar J. 2021. PMID: 33608006 Free PMC article.
BACKGROUND: The diagnosis of malaria cases in regions where the malaria burden has decreased significantly and prevalence is very low is more challenging, in part because of reduced clinical presumption of malaria. The appearance of a cluster of malaria
BACKGROUND: The diagnosis of malaria cases in regions where the malaria burden has decreased significantly and prevalence is v …
Application of genomics to field investigations of malaria by the international centers of excellence for malaria research.
Volkman SK, Ndiaye D, Diakite M, Koita OA, Nwakanma D, Daniels RF, Park DJ, Neafsey DE, Muskavitch MA, Krogstad DJ, Sabeti PC, Hartl DL, Wirth DF. Volkman SK, et al. Acta Trop. 2012 Mar;121(3):324-32. doi: 10.1016/j.actatropica.2011.12.002. Epub 2011 Dec 13. Acta Trop. 2012. PMID: 22182668 Free PMC article. Review.
Success of the global research agenda toward eradication of malaria will depend on development of new tools, including drugs, vaccines, insecticides and diagnostics. ...Although knowledge of genomic sequences for the malaria parasites, Plasmodium falciparum and Plas …
Success of the global research agenda toward eradication of malaria will depend on development of new tools, including drugs, vaccine …
Comparative evolutionary genomics of human malaria parasites.
Carlton JM, Escalante AA, Neafsey D, Volkman SK. Carlton JM, et al. Trends Parasitol. 2008 Dec;24(12):545-50. doi: 10.1016/j.pt.2008.09.003. Epub 2008 Oct 18. Trends Parasitol. 2008. PMID: 18938107 Review.
The parasites Plasmodium falciparum and Plasmodium vivax are responsible for the majority of human malaria cases worldwide. Despite many similarities in their biology, they frequently are studied in isolation. ...Here, we briefly review our current knowledge of comparative …
The parasites Plasmodium falciparum and Plasmodium vivax are responsible for the majority of human malaria cases worldwide. Despite m …
Evidence of non-Plasmodium falciparum malaria infection in Kédougou, Sénégal.
Daniels RF, Deme AB, Gomis JF, Dieye B, Durfee K, Thwing JI, Fall FB, Ba M, Ndiop M, Badiane AS, Ndiaye YD, Wirth DF, Volkman SK, Ndiaye D. Daniels RF, et al. Malar J. 2017 Jan 3;16(1):9. doi: 10.1186/s12936-016-1661-3. Malar J. 2017. PMID: 28049489 Free PMC article.
However, the type of RDT utilized in Senegal does not detect other malaria-causing species such as Plasmodium ovale spp., Plasmodium malariae, or Plasmodium vivax. ...CONCLUSIONS: These findings emphasize the limitations of the RDT used for malaria diagnosis …
However, the type of RDT utilized in Senegal does not detect other malaria-causing species such as Plasmodium ovale spp., Plasmodium …
Genome-Wide Association Studies of Drug-Resistance Determinants.
Volkman SK, Herman J, Lukens AK, Hartl DL. Volkman SK, et al. Trends Parasitol. 2017 Mar;33(3):214-230. doi: 10.1016/j.pt.2016.10.001. Epub 2016 Oct 27. Trends Parasitol. 2017. PMID: 28179098 Review.
However, challenges and limitations persist in identifying drug-resistance loci in malaria. In this review we discuss the genetic basis of drug resistance and the use of genome-wide association studies, complemented by selection and linkage studies, to identify and underst …
However, challenges and limitations persist in identifying drug-resistance loci in malaria. In this review we discuss the genetic bas …
Genetic evidence for imported malaria and local transmission in Richard Toll, Senegal.
Daniels RF, Schaffner SF, Dieye Y, Dieng G, Hainsworth M, Fall FB, Diouf CN, Ndiop M, Cisse M, Gueye AB, Sarr O, Guinot P, Deme AB, Bei AK, Sy M, Thwing J, MacInnis B, Earle D, Guinovart C, Sene D, Hartl DL, Ndiaye D, Steketee RW, Wirth DF, Volkman SK. Daniels RF, et al. Malar J. 2020 Aug 3;19(1):276. doi: 10.1186/s12936-020-03346-x. Malar J. 2020. PMID: 32746830 Free PMC article.
BACKGROUND: Malaria elimination efforts can be undermined by imported malaria infections. ...CONCLUSIONS: These data indicate that, while a large number of infections may have been imported, there remains ongoing local malaria transmission in Richard Toll. Th …
BACKGROUND: Malaria elimination efforts can be undermined by imported malaria infections. ...CONCLUSIONS: These data indicate …
Volkman's Contracture, Persistent Limb Ischaemia, and Amputation: A Complication of Brachial Artery Catheterisation for Haemodynamic Monitoring Using PiCCO.
Bagga V, Palmer M, Sadasivan R, Raghuraman G. Bagga V, et al. Case Rep Crit Care. 2013;2013:474358. doi: 10.1155/2013/474358. Epub 2013 Sep 26. Case Rep Crit Care. 2013. PMID: 24829826 Free PMC article.
We report a case of a 64-year-old woman who was admitted to intensive care unit with multiorgan failure secondary to Plasmodium falciparum malaria. Haemodynamic monitoring using the transpulmonary thermodilution with pulse contour analysis system (PiCCO) was achieved via t …
We report a case of a 64-year-old woman who was admitted to intensive care unit with multiorgan failure secondary to Plasmodium falciparum …
Barriers to malaria prevention among immigrant travelers in the United States who visit friends and relatives in sub-Saharan Africa: A cross-sectional, multi-setting survey of knowledge, attitudes, and practices.
Volkman HR, Walz EJ, Wanduragala D, Schiffman E, Frosch A, Alpern JD, Walker PF, Angelo KM, Coyle C, Mohamud MA, Mwangi E, Haizel-Cobbina J, Nchanji C, Johnson RS, Ladze B, Dunlop SJ, Stauffer WM. Volkman HR, et al. PLoS One. 2020 Mar 12;15(3):e0229565. doi: 10.1371/journal.pone.0229565. eCollection 2020. PLoS One. 2020. PMID: 32163426 Free PMC article.
BACKGROUND: Despite achievements in the reduction of malaria globally, imported malaria cases to the United States by returning international travelers continue to increase. ...VFRs who reported taking antimalarials on their last trip rated their concern about ma
BACKGROUND: Despite achievements in the reduction of malaria globally, imported malaria cases to the United States by returnin …
98 results