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The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes.
Vonderheide RH, Hahn WC, Schultze JL, Nadler LM. Vonderheide RH, et al. Immunity. 1999 Jun;10(6):673-9. doi: 10.1016/s1074-7613(00)80066-7. Immunity. 1999. PMID: 10403642
RNA-loaded CD40-activated B cells stimulate antigen-specific T-cell responses in dogs with spontaneous lymphoma.
Mason NJ, Coughlin CM, Overley B, Cohen JN, Mitchell EL, Colligon TA, Clifford CA, Zurbriggen A, Sorenmo KU, Vonderheide RH. Mason NJ, et al. Among authors: vonderheide rh. Gene Ther. 2008 Jul;15(13):955-65. doi: 10.1038/gt.2008.22. Epub 2008 Mar 13. Gene Ther. 2008. PMID: 18337841
Universal tumor antigens as targets for immunotherapy.
Gordan JD, Vonderheide RH. Gordan JD, et al. Among authors: vonderheide rh. Cytotherapy. 2002;4(4):317-27. doi: 10.1080/146532402760271091. Cytotherapy. 2002. PMID: 12396831 Review.
Rare naturally occurring immune responses to three epitopes from the widely expressed tumour antigens hTERT and CYP1B1 in multiple myeloma patients.
Maecker B, von Bergwelt-Baildon MS, Anderson KS, Vonderheide RH, Anderson KC, Nadler LM, Schultze JL. Maecker B, et al. Among authors: vonderheide rh. Clin Exp Immunol. 2005 Sep;141(3):558-62. doi: 10.1111/j.1365-2249.2005.02879.x. Clin Exp Immunol. 2005. PMID: 16045747 Free PMC article.
Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals.
Vonderheide RH, Schultze JL, Anderson KS, Maecker B, Butler MO, Xia Z, Kuroda MJ, von Bergwelt-Baildon MS, Bedor MM, Hoar KM, Schnipper DR, Brooks MW, Letvin NL, Stephans KF, Wucherpfennig KW, Hahn WC, Nadler LM. Vonderheide RH, et al. Cancer Res. 2001 Dec 1;61(23):8366-70. Cancer Res. 2001. PMID: 11731409
Linking genomics to immunotherapy by reverse immunology--'immunomics' in the new millennium.
Maecker B, von Bergwelt-Baildon, Anderson KS, Vonderheide RH, Schultze JL. Maecker B, et al. Among authors: vonderheide rh. Curr Mol Med. 2001 Nov;1(5):609-19. doi: 10.2174/1566524013363447. Curr Mol Med. 2001. PMID: 11899235 Review.
Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies.
Trojan A, Schultze JL, Witzens M, Vonderheide RH, Ladetto M, Donovan JW, Gribben JG. Trojan A, et al. Among authors: vonderheide rh. Nat Med. 2000 Jun;6(6):667-72. doi: 10.1038/76243. Nat Med. 2000. PMID: 10835683
Generation of cytotoxic T lymphocytes against native and altered peptides of human leukocyte antigen-A*0201 restricted epitopes from the human epithelial cell adhesion molecule.
Trojan A, Witzens M, Schultze JL, Vonderheide RH, Harig S, Krackhardt AM, Stahel RA, Gribben JG. Trojan A, et al. Among authors: vonderheide rh. Cancer Res. 2001 Jun 15;61(12):4761-5. Cancer Res. 2001. PMID: 11406549
Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase.
Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, Nadler LM. Vonderheide RH, et al. Clin Cancer Res. 2001 Nov;7(11):3343-8. Clin Cancer Res. 2001. PMID: 11705846
CD40 activation of carcinoma cells increases expression of adhesion and major histocompatibility molecules but fails to induce either CD80/CD86 expression or T cell alloreactivity.
Vonderheide RH, Butler MO, Liu JF, Battle TE, Hirano N, Gribben JG, Frank DA, Schultze JL, Nadler LM. Vonderheide RH, et al. Int J Oncol. 2001 Oct;19(4):791-8. doi: 10.3892/ijo.19.4.791. Int J Oncol. 2001. PMID: 11562757
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