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Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.
Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E. Anggakusuma, et al. Among authors: vondran fw. Hepatology. 2015 Sep;62(3):702-14. doi: 10.1002/hep.27913. Epub 2015 Jul 28. Hepatology. 2015. PMID: 25999047
Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses.
Hueging K, Weller R, Doepke M, Vieyres G, Todt D, Wölk B, Vondran FW, Geffers R, Lauber C, Kaderali L, Penin F, Pietschmann T. Hueging K, et al. Among authors: vondran fw. PLoS One. 2015 Jul 30;10(7):e0134529. doi: 10.1371/journal.pone.0134529. eCollection 2015. PLoS One. 2015. PMID: 26226615 Free PMC article.
Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.
Perin PM, Haid S, Brown RJ, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FW, Speerstra S, Awadh A, Mukhtarov F, Schang LM, Kirschning A, Müller R, Guzman CA, Kaderali L, Randall G, Meuleman P, Ploss A, Pietschmann T. Perin PM, et al. Among authors: vondran fw. Hepatology. 2016 Jan;63(1):49-62. doi: 10.1002/hep.28111. Epub 2015 Oct 9. Hepatology. 2016. PMID: 26248546 Free PMC article.
Host cell mTORC1 is required for HCV RNA replication.
Stöhr S, Costa R, Sandmann L, Westhaus S, Pfaender S, Anggakusuma, Dazert E, Meuleman P, Vondran FW, Manns MP, Steinmann E, von Hahn T, Ciesek S. Stöhr S, et al. Among authors: vondran fw. Gut. 2016 Dec;65(12):2017-2028. doi: 10.1136/gutjnl-2014-308971. Epub 2015 Aug 14. Gut. 2016. PMID: 26276683 Free PMC article.
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture.
Harak C, Meyrath M, Romero-Brey I, Schenk C, Gondeau C, Schult P, Esser-Nobis K, Saeed M, Neddermann P, Schnitzler P, Gotthardt D, Perez-Del-Pulgar S, Neumann-Haefelin C, Thimme R, Meuleman P, Vondran FW, De Francesco R, Rice CM, Bartenschlager R, Lohmann V. Harak C, et al. Among authors: vondran fw. Nat Microbiol. 2016 Dec 19;2:16247. doi: 10.1038/nmicrobiol.2016.247. Nat Microbiol. 2016. PMID: 27991882
158 results