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Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
Vos M, Esposito G, Edirisinghe JN, Vilain S, Haddad DM, Slabbaert JR, Van Meensel S, Schaap O, De Strooper B, Meganathan R, Morais VA, Verstreken P. Vos M, et al. Science. 2012 Jun 8;336(6086):1306-10. doi: 10.1126/science.1218632. Epub 2012 May 10. Science. 2012. PMID: 22582012 Free article.
The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.
Vilain S, Esposito G, Haddad D, Schaap O, Dobreva MP, Vos M, Van Meensel S, Morais VA, De Strooper B, Verstreken P. Vilain S, et al. Among authors: vos m. PLoS Genet. 2012 Jan;8(1):e1002456. doi: 10.1371/journal.pgen.1002456. Epub 2012 Jan 5. PLoS Genet. 2012. PMID: 22242018 Free PMC article.
Aconitase causes iron toxicity in Drosophila pink1 mutants.
Esposito G, Vos M, Vilain S, Swerts J, De Sousa Valadas J, Van Meensel S, Schaap O, Verstreken P. Esposito G, et al. Among authors: vos m. PLoS Genet. 2013 Apr;9(4):e1003478. doi: 10.1371/journal.pgen.1003478. Epub 2013 Apr 25. PLoS Genet. 2013. PMID: 23637640 Free PMC article.
Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy.
Haddad DM, Vilain S, Vos M, Esposito G, Matta S, Kalscheuer VM, Craessaerts K, Leyssen M, Nascimento RM, Vianna-Morgante AM, De Strooper B, Van Esch H, Morais VA, Verstreken P. Haddad DM, et al. Among authors: vos m. Mol Cell. 2013 Jun 27;50(6):831-43. doi: 10.1016/j.molcel.2013.04.012. Epub 2013 May 16. Mol Cell. 2013. PMID: 23685073 Free article.
CEP89 is required for mitochondrial metabolism and neuronal function in man and fly.
van Bon BW, Oortveld MA, Nijtmans LG, Fenckova M, Nijhof B, Besseling J, Vos M, Kramer JM, de Leeuw N, Castells-Nobau A, Asztalos L, Viragh E, Ruiter M, Hofmann F, Eshuis L, Collavin L, Huynen MA, Asztalos Z, Verstreken P, Rodenburg RJ, Smeitink JA, de Vries BB, Schenck A. van Bon BW, et al. Among authors: vos m. Hum Mol Genet. 2013 Aug 1;22(15):3138-51. doi: 10.1093/hmg/ddt170. Epub 2013 Apr 10. Hum Mol Genet. 2013. PMID: 23575228
2,478 results