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Frequency analysis of tumor-reactive cytotoxic T lymphocytes in peripheral blood of a melanoma patient vaccinated with autologous tumor cells.
Herr W, Wölfel T, Heike M, Meyer zum Büschenfelde KH, Knuth A. Herr W, et al. Cancer Immunol Immunother. 1994 Aug;39(2):93-9. doi: 10.1007/BF01525314. Cancer Immunol Immunother. 1994. PMID: 8044834
A limiting-dilution assay was developed and used to determine the frequency of autologous tumor-reactive cytotoxic T lymphocytes (CTL) in peripheral blood of a melanoma patient MZ2, who has been free of detectable disease since several years. ...We conclude, that the limit …
A limiting-dilution assay was developed and used to determine the frequency of autologous tumor-reactive cytotoxic T lymphocytes (CTL …
T cell responses to human malignant tumours.
Knuth A, Wölfel T, Meyer zum Büschenfelde KH. Knuth A, et al. Cancer Surv. 1992;13:39-52. Cancer Surv. 1992. PMID: 1423325 Review.
The immunological and molecular mechanisms that govern T cell responses to human malignant tumours are just starting to be understood within a more complex framework of humoral, cellular and molecular interactions. The definition of multiple antigens simultaneously express …
The immunological and molecular mechanisms that govern T cell responses to human malignant tumours are just starting to be understood …
Cellular and humoral immune responses against cancer: implications for cancer vaccines.
Knuth A, Wölfel T, Meyer zum Büschenfelde KH. Knuth A, et al. Curr Opin Immunol. 1991 Oct;3(5):659-64. doi: 10.1016/0952-7915(91)90093-g. Curr Opin Immunol. 1991. PMID: 1755985 Review.
Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.
Knuth A, Wölfel T, Klehmann E, Boon T, Meyer zum Büschenfelde KH. Knuth A, et al. Proc Natl Acad Sci U S A. 1989 Apr;86(8):2804-8. doi: 10.1073/pnas.86.8.2804. Proc Natl Acad Sci U S A. 1989. PMID: 2784858 Free PMC article.
Cytolytic T-lymphocyte (CTL) clones against an autologous melanoma (SK-MEL-29) were generated by mixed lymphocyte tumor culture and subsequent cloning of responder lymphocytes at limiting dilutions. ...
Cytolytic T-lymphocyte (CTL) clones against an autologous melanoma (SK-MEL-29) were generated by mixed lymphocyte tumor culture and s …
Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens.
Wölfel T, Klehmann E, Müller C, Schütt KH, Meyer zum Büschenfelde KH, Knuth A. Wölfel T, et al. J Exp Med. 1989 Sep 1;170(3):797-810. doi: 10.1084/jem.170.3.797. J Exp Med. 1989. PMID: 2788708 Free PMC article.
From the peripheral blood of the melanoma patient (AV), we derived cytolytic T lymphocyte (CTL) clones that lysed the autologous tumor line SK-MEL-29, but not autologous EBV-B cells, K562, and other tumor targets. ...
From the peripheral blood of the melanoma patient (AV), we derived cytolytic T lymphocyte (CTL) clones that lysed the autologous tumo …
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma.
Wölfel T, Hauer M, Schneider J, Serrano M, Wölfel C, Klehmann-Hieb E, De Plaen E, Hankeln T, Meyer zum Büschenfelde KH, Beach D. Wölfel T, et al. Science. 1995 Sep 1;269(5228):1281-4. doi: 10.1126/science.7652577. Science. 1995. PMID: 7652577
A mutated cyclin-dependent kinase 4 (CDK4) was identified as a tumor-specific antigen recognized by HLA-A2. 1-restricted autologous cytolytic T lymphocytes (CTLs) in a human melanoma. ...
A mutated cyclin-dependent kinase 4 (CDK4) was identified as a tumor-specific antigen recognized by HLA-A2. 1-restricted autologous cytolyti …
Induction of tumour cell lysis by a bispecific antibody recognising epidermal growth factor receptor (EGFR) and CD3.
Knuth A, Bernhard H, Jäger E, Wölfel T, Karbach J, Jäggle C, Strittmatter W, Meyer zum Büschenfelde KH. Knuth A, et al. Eur J Cancer. 1994;30A(8):1103-7. doi: 10.1016/0959-8049(94)90466-9. Eur J Cancer. 1994. PMID: 7654439
Analysis of antigens recognized on human melanoma cells by A2-restricted cytolytic T lymphocytes (CTL).
Wölfel T, Hauer M, Klehmann E, Brichard V, Ackermann B, Knuth A, Boon T, Meyer Zum Büschenfelde KH. Wölfel T, et al. Int J Cancer. 1993 Sep 9;55(2):237-44. doi: 10.1002/ijc.2910550212. Int J Cancer. 1993. PMID: 7690346
We have pursued our analysis of potential tumor-rejection antigens recognized on human melanoma by autologous cytolytic T lymphocytes (CTL). ...
We have pursued our analysis of potential tumor-rejection antigens recognized on human melanoma by autologous cytolytic T lymphocytes …
Sustained elimination of hepatitis B virus from serum induced in a patient with chronic hepatitis B and advanced human immunodeficiency virus infection.
Wölfel T, Schirmacher P, Schlaak J, Knolle P, Dienes HP, Dippold W, Meyer zum Büschenfelde KH, Gerken G. Wölfel T, et al. Clin Investig. 1994 Dec;72(12):1030-6. doi: 10.1007/BF00577750. Clin Investig. 1994. PMID: 7711410
Cytotoxic T-lymphocyte clones from different patients display limited T-cell-receptor variable-region gene usage in HLA-A2-restricted recognition of the melanoma antigen Melan-A/MART-1.
Sensi M, Traversari C, Radrizzani M, Salvi S, Maccalli C, Mortarini R, Rivoltini L, Farina C, Nicolini G, Wölfel T, et al. Sensi M, et al. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5674-8. doi: 10.1073/pnas.92.12.5674. Proc Natl Acad Sci U S A. 1995. PMID: 7777568 Free PMC article.
To determine whether T-cell-receptor (TCR) usage by T cells recognizing a defined human tumor antigen in the context of the same HLA molecule is conserved, we analyzed the TCR diversity of autologous HLA-A2-restricted cytotoxic T-lymphocyte (CTL) clones deriv …
To determine whether T-cell-receptor (TCR) usage by T cells recognizing a defined human tumor antigen in the context of the sa …
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