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Showing results for wide and hoff
Search for Waade and Hoff instead (1 results)
Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study.
Nethander M, Coward E, Reimann E, Grahnemo L, Gabrielsen ME, Wibom C; Estonian Biobank Research Team; Mägi R, Funck-Brentano T, Hoff M, Langhammer A, Pettersson-Kymmer U, Hveem K, Ohlsson C. Nethander M, et al. Cell Rep Med. 2022 Oct 18;3(10):100776. doi: 10.1016/j.xcrm.2022.100776. Cell Rep Med. 2022. PMID: 36260985 Free PMC article.
Here, we perform a large-scale hip fracture genome-wide association study meta-analysis and Mendelian randomization study using five cohorts from European biobanks. ...
Here, we perform a large-scale hip fracture genome-wide association study meta-analysis and Mendelian randomization study using five …
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing.
Sifrim A, Hitz MP, Wilsdon A, Breckpot J, Turki SH, Thienpont B, McRae J, Fitzgerald TW, Singh T, Swaminathan GJ, Prigmore E, Rajan D, Abdul-Khaliq H, Banka S, Bauer UM, Bentham J, Berger F, Bhattacharya S, Bu'Lock F, Canham N, Colgiu IG, Cosgrove C, Cox H, Daehnert I, Daly A, Danesh J, Fryer A, Gewillig M, Hobson E, Hoff K, Homfray T; INTERVAL Study; Kahlert AK, Ketley A, Kramer HH, Lachlan K, Lampe AK, Louw JJ, Manickara AK, Manase D, McCarthy KP, Metcalfe K, Moore C, Newbury-Ecob R, Omer SO, Ouwehand WH, Park SM, Parker MJ, Pickardt T, Pollard MO, Robert L, Roberts DJ, Sambrook J, Setchfield K, Stiller B, Thornborough C, Toka O, Watkins H, Williams D, Wright M, Mital S, Daubeney PE, Keavney B, Goodship J; UK10K Consortium; Abu-Sulaiman RM, Klaassen S, Wright CF, Firth HV, Barrett JC, Devriendt K, FitzPatrick DR, Brook JD; Deciphering Developmental Disorders Study; Hurles ME. Sifrim A, et al. Nat Genet. 2016 Sep;48(9):1060-5. doi: 10.1038/ng.3627. Epub 2016 Aug 1. Nat Genet. 2016. PMID: 27479907 Free PMC article.
Conversely, in NS-CHD we observed significant enrichment of PTVs inherited from unaffected parents in CHD-associated genes. We identified three genome-wide significant S-CHD disorders caused by DNMs in CHD4, CDK13 and PRKD1. Our study finds evidence for distinct genetic ar …
Conversely, in NS-CHD we observed significant enrichment of PTVs inherited from unaffected parents in CHD-associated genes. We identified th …
Our future in the Anthropocene biosphere.
Folke C, Polasky S, Rockström J, Galaz V, Westley F, Lamont M, Scheffer M, Österblom H, Carpenter SR, Chapin FS 3rd, Seto KC, Weber EU, Crona BI, Daily GC, Dasgupta P, Gaffney O, Gordon LJ, Hoff H, Levin SA, Lubchenco J, Steffen W, Walker BH. Folke C, et al. Ambio. 2021 Apr;50(4):834-869. doi: 10.1007/s13280-021-01544-8. Epub 2021 Mar 14. Ambio. 2021. PMID: 33715097 Free PMC article. Review.
The Anthropocene reality-of rising system-wide turbulence-calls for transformative change towards sustainable futures. Emerging technologies, social innovations, broader shifts in cultural repertoires, as well as a diverse portfolio of active stewardship of human actions i …
The Anthropocene reality-of rising system-wide turbulence-calls for transformative change towards sustainable futures. Emerging techn …
Evaluation of suitability and detection range of fluorescent dye-loaded nanoliposomes for sensitive and rapid sensing of wide ranging osmolarities.
Roy D, Udugiri GHS, Ranganath SH. Roy D, et al. J Liposome Res. 2023 Sep;33(3):300-313. doi: 10.1080/08982104.2023.2172582. Epub 2023 Feb 6. J Liposome Res. 2023. PMID: 36744858
F(Green)/F(Red) decreased linearly with increasing osmolarity, obeying Boyle van't Hoff's relationship, thus proving that the nanoliposomes are osmosensitive. A calibration curve was generated to compute osmolarity based on F(Green)/F(Red) measurements. ...Thus, the nanoli …
F(Green)/F(Red) decreased linearly with increasing osmolarity, obeying Boyle van't Hoff's relationship, thus proving that the nanolip …
An atlas of genetic determinants of forearm fracture.
Nethander M, Movérare-Skrtic S, Kämpe A, Coward E, Reimann E, Grahnemo L, Borbély É, Helyes Z, Funck-Brentano T, Cohen-Solal M, Tuukkanen J, Koskela A, Wu J, Li L, Lu T, Gabrielsen ME; Estonian Biobank Research Team; Mägi R, Hoff M, Lerner UH, Henning P, Ullum H, Erikstrup C, Brunak S; DBDS Genomic Consortium; Langhammer A, Tuomi T, Oddsson A, Stefansson K, Pettersson-Kymmer U, Ostrowski SR, Pedersen OBV, Styrkarsdottir U, Mäkitie O, Hveem K, Richards JB, Ohlsson C. Nethander M, et al. Nat Genet. 2023 Nov;55(11):1820-1830. doi: 10.1038/s41588-023-01527-3. Epub 2023 Nov 2. Nat Genet. 2023. PMID: 37919453 Free PMC article.
To establish an atlas of the genetic determinants of forearm fractures, we performed genome-wide association analyses including 100,026 forearm fracture cases. We identified 43 loci, including 26 new fracture loci. ...
To establish an atlas of the genetic determinants of forearm fractures, we performed genome-wide association analyses including 100,0 …
Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Blandino Ortiz A, de Salazar A, Garrido Chercoles A, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A, Holten AR, Mayer A, Bandera A, Cherubini A, Protti A, Aghemo A, Gerussi A, Ramirez A, Braun A, Nebel A, Barreira A, Lleo A, Teles A, Kildal AB, Biondi A, Caballero-Garralda A, Ganna A, Gori A, Glück A, Lind A, Tanck A, Hinney A, Carreras Nolla A, Fracanzani AL, Peschuck A, Cavallero A, Dyrhol-Riise AM, Ruello A, Julià A, Muscatello A, Pesenti A, Voza A, Rando-Segura A, Solier A, Schmidt A, Cortes B, Mateos B, Nafria-Jimenez B, Schaefer B, Jensen B, Bellinghausen C, Maj C, Ferrando C, de la Horra C, Quereda C, Skurk C, Thibeault C, Scollo C, Herr C, Spinner CD, Gassner C, Lange C, Hu C, Paccapelo C, Lehmann C, Angelini C, Cappadona C, Azuure C; COVICAT study group, Aachen Study (COVAS); Bianco C, Cea C, Sancho C, Hoff DAL, Galimberti D, Prati D, Haschka D, Jiménez D, Pestaña D, Toapanta D, Muñiz-Diaz E, Azzolini E, Sandoval E, Binatti E, Scarpini E, Helbig ET, Ca… See abstract for full author list ➔ Degenhardt F, et al. Hum Mol Genet. 2022 Nov 28;31(23):3945-3966. doi: 10.1093/hmg/ddac158. Hum Mol Genet. 2022. PMID: 35848942 Free PMC article.
Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease mechanisms. Here, we describe an extended genome-wide …
Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to s …
Rare embryonal and sarcomatous central nervous system tumours: State-of-the art and future directions.
Gojo J, Kjaersgaard M, Zezschwitz BV, Capper D, Tietze A, Kool M, Haberler C, Pizer B, Hoff KV. Gojo J, et al. Eur J Med Genet. 2023 Jan;66(1):104660. doi: 10.1016/j.ejmg.2022.104660. Epub 2022 Nov 7. Eur J Med Genet. 2023. PMID: 36356895 Free article. Review.
By emphasizing the significant consequences on patient management in paediatric CNS tumours, we want to encourage wide implementation of comprehensive molecular diagnostics and stress the importance for joint international efforts to further collect and study these rare tu …
By emphasizing the significant consequences on patient management in paediatric CNS tumours, we want to encourage wide implementation …
Critical Assessment of the Chemical Space Covered by LC-HRMS Non-Targeted Analysis.
Hulleman T, Turkina V, O'Brien JW, Chojnacka A, Thomas KV, Samanipour S. Hulleman T, et al. Environ Sci Technol. 2023 Sep 26;57(38):14101-14112. doi: 10.1021/acs.est.3c03606. Epub 2023 Sep 13. Environ Sci Technol. 2023. PMID: 37704971 Free PMC article. Review.
Even though they are generic and have a wide scope, non-targeted analysis methods have been shown to have limitations in terms of their coverage of the chemical space, as the number of identified chemicals in each sample is very low (e.g., 5%). ...Little to no trend was fo …
Even though they are generic and have a wide scope, non-targeted analysis methods have been shown to have limitations in terms of the …
Monitoring TGFβ signaling in irradiated tumors.
Ma L, Gonzalez-Junca A, Chou W, Barcellos-Hoff MH. Ma L, et al. Methods Cell Biol. 2023;180:49-67. doi: 10.1016/bs.mcb.2023.02.009. Epub 2023 Jun 9. Methods Cell Biol. 2023. PMID: 37890932
Ionizing radiation elicits rapid release of TGFbeta from these stores, so-called activation, over a wide range of doses and exposures, including low dose (<1Gy) whole-body irradiation, creating an extraordinarily potent signal in the irradiated tissue or tumor. ...
Ionizing radiation elicits rapid release of TGFbeta from these stores, so-called activation, over a wide range of doses and exposures …
Descriptions of Disordered Eating in German Psychiatric Textbooks, 1803-2017.
Bergner L, Himmerich H, Kirkby KC, Steinberg H. Bergner L, et al. Front Psychiatry. 2021 Jan 14;11:504157. doi: 10.3389/fpsyt.2020.504157. eCollection 2020. Front Psychiatry. 2021. PMID: 33519534 Free PMC article.
Interestingly, 19th and early 20th century psychiatrists like Kraepelin, Bumke, Hoff, Bleuler, and Jaspers reported symptom clusters such as food refusal and vomiting under these outdated diagnostic categories, whereas nowadays they are listed as core criteria for specific …
Interestingly, 19th and early 20th century psychiatrists like Kraepelin, Bumke, Hoff, Bleuler, and Jaspers reported symptom clusters …
335 results