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Targeting inhaled fibers to the pulmonary acinus: Opportunities for augmented delivery from in silico simulations.
Shachar-Berman L, Ostrovski Y, Koshiyama K, Wada S, Kassinos SC, Sznitman J. Shachar-Berman L, et al. Among authors: wada s. Eur J Pharm Sci. 2019 Sep 1;137:105003. doi: 10.1016/j.ejps.2019.105003. Epub 2019 Jul 11. Eur J Pharm Sci. 2019. PMID: 31302212
One (sub-)acinus for all: Fate of inhaled aerosols in heterogeneous pulmonary acinar structures.
Hofemeier P, Koshiyama K, Wada S, Sznitman J. Hofemeier P, et al. Among authors: wada s. Eur J Pharm Sci. 2018 Feb 15;113:53-63. doi: 10.1016/j.ejps.2017.09.033. Epub 2017 Sep 24. Eur J Pharm Sci. 2018. PMID: 28954217 Free PMC article. Review.
Our heterogeneous acinar domains represent complete sub-acinar models (i.e. 1/8th of a full acinus) based on the recent algorithm of Koshiyama & Wada (2015), capturing statistics of human acinar morphometry (Ochs et al. 2004). ...
Our heterogeneous acinar domains represent complete sub-acinar models (i.e. 1/8th of a full acinus) based on the recent algorithm of Koshiya …
Heterogeneous structure and surface tension effects on mechanical response in pulmonary acinus: A finite element analysis.
Koshiyama K, Nishimoto K, Ii S, Sera T, Wada S. Koshiyama K, et al. Among authors: wada s. Clin Biomech (Bristol, Avon). 2019 Jun;66:32-39. doi: 10.1016/j.clinbiomech.2018.01.001. Epub 2018 Jan 20. Clin Biomech (Bristol, Avon). 2019. PMID: 29370949
Mathematical model of a heterogeneous pulmonary acinus structure.
Koshiyama K, Wada S. Koshiyama K, et al. Among authors: wada s. Comput Biol Med. 2015 Jul;62:25-32. doi: 10.1016/j.compbiomed.2015.03.032. Epub 2015 Apr 14. Comput Biol Med. 2015. PMID: 25912985
Morphological Characterization of Acinar Cluster in Mouse Lung Using a Multiscale-based Segmentation Algorithm on Synchrotron Micro-CT Images.
Xiao L, Sera T, Koshiyama K, Wada S. Xiao L, et al. Among authors: wada s. Anat Rec (Hoboken). 2016 Oct;299(10):1424-34. doi: 10.1002/ar.23452. Epub 2016 Aug 12. Anat Rec (Hoboken). 2016. PMID: 27488590
Model-based inverse estimation for active contraction stresses of tongue muscles using 3D surface shape in speech production.
Koike N, Ii S, Yoshinaga T, Nozaki K, Wada S. Koike N, et al. Among authors: wada s. J Biomech. 2017 Nov 7;64:69-76. doi: 10.1016/j.jbiomech.2017.09.008. Epub 2017 Sep 14. J Biomech. 2017. PMID: 28947160
Collapse of a lipid-coated nanobubble and subsequent liposome formation.
Koshiyama K, Wada S. Koshiyama K, et al. Among authors: wada s. Sci Rep. 2016 Jun 16;6:28164. doi: 10.1038/srep28164. Sci Rep. 2016. PMID: 27306704 Free PMC article.
A semiautomatic segmentation algorithm for extracting the complete structure of acini from synchrotron micro-CT images.
Xiao L, Sera T, Koshiyama K, Wada S. Xiao L, et al. Among authors: wada s. Comput Math Methods Med. 2013;2013:575086. doi: 10.1155/2013/575086. Epub 2013 Feb 28. Comput Math Methods Med. 2013. PMID: 23533543 Free PMC article.
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