Wade H - Search Results

1

Charge is Major Determinant of Activation of the Ligand-Responsive Multidrug Resistance Gene Regulator, BmrR.

Bachas S, Kohrs B, Wade H. Bachas S, et al. Among authors: wade h. ChemMedChem. 2016 May 19;11(10):1038-41. doi: 10.1002/cmdc.201600059. Epub 2016 Mar 24. ChemMedChem. 2016. PMID: 27010425

2

Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR.

Bachas S, Eginton C, Gunio D, Wade H. Bachas S, et al. Among authors: wade h. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11046-51. doi: 10.1073/pnas.1104850108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690368 Free PMC article.

3

Unconventional Coupling between Ligand Recognition and Allosteric Control in the Multidrug Resistance Gene Regulator, BmrR.

Bachas S, Kohrs B, Wade H. Bachas S, et al. Among authors: wade h. ChemMedChem. 2017 Mar 17;12(6):426-430. doi: 10.1002/cmdc.201700017. Epub 2017 Feb 14. ChemMedChem. 2017. PMID: 28090749

4

Allosteric coupling via distant disorder-to-order transitions.

Eginton C, Cressman WJ, Bachas S, Wade H, Beckett D. Eginton C, et al. Among authors: wade h. J Mol Biol. 2015 Apr 24;427(8):1695-704. doi: 10.1016/j.jmb.2015.02.021. Epub 2015 Mar 4. J Mol Biol. 2015. PMID: 25746672

5

Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.

Moreno A, Froehlig JR, Bachas S, Gunio D, Alexander T, Vanya A, Wade H. Moreno A, et al. Among authors: wade h. Biochemistry. 2016 Aug 30;55(34):4850-63. doi: 10.1021/acs.biochem.6b00651. Epub 2016 Aug 18. Biochemistry. 2016. PMID: 27505298

6

Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR): Efavirenz and 8-Hydroxyefavirenz Exhibit Divergence in Activation.

Narayanan B, Lade JM, Heck CJS, Dietz KD, Wade H, Bumpus NN. Narayanan B, et al. Among authors: wade h. ChemMedChem. 2018 Apr 6;13(7):736-747. doi: 10.1002/cmdc.201700730. Epub 2018 Mar 2. ChemMedChem. 2018. PMID: 29430850 Free PMC article.

7

Solution-Binding and Molecular Docking Approaches Combine to Provide an Expanded View of Multidrug Recognition in the MDR Gene Regulator BmrR.

Gunio D, Froehlig J, Pappas K, Ferguson U, Wade H. Gunio D, et al. Among authors: wade h. J Chem Inf Model. 2016 Feb 22;56(2):377-89. doi: 10.1021/acs.jcim.5b00704. Epub 2016 Feb 8. J Chem Inf Model. 2016. PMID: 26820041

8

MD recognition by MDR gene regulators.

Wade H. Wade H. Curr Opin Struct Biol. 2010 Aug;20(4):489-96. doi: 10.1016/j.sbi.2010.06.003. Epub 2010 Jun 26. Curr Opin Struct Biol. 2010. PMID: 20580544 Review.

9

1-Deoxy-D-xylulose 5-phosphate synthase catalyzes a novel random sequential mechanism.

Brammer LA, Smith JM, Wade H, Meyers CF. Brammer LA, et al. Among authors: wade h. J Biol Chem. 2011 Oct 21;286(42):36522-31. doi: 10.1074/jbc.M111.259747. Epub 2011 Aug 30. J Biol Chem. 2011. PMID: 21878632 Free PMC article.

10

Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling.

Hu S, Xie Z, Onishi A, Yu X, Jiang L, Lin J, Rho HS, Woodard C, Wang H, Jeong JS, Long S, He X, Wade H, Blackshaw S, Qian J, Zhu H. Hu S, et al. Among authors: wade h. Cell. 2009 Oct 30;139(3):610-22. doi: 10.1016/j.cell.2009.08.037. Cell. 2009. PMID: 19879846 Free PMC article.

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