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The IL-6/sIL-6R complex as a novel target for therapeutic approaches.
Rose-John S, Waetzig GH, Scheller J, Grötzinger J, Seegert D. Rose-John S, et al. Among authors: waetzig gh. Expert Opin Ther Targets. 2007 May;11(5):613-24. doi: 10.1517/14728222.11.5.613. Expert Opin Ther Targets. 2007. PMID: 17465721 Review.
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays.
Costello CM, Mah N, Häsler R, Rosenstiel P, Waetzig GH, Hahn A, Lu T, Gurbuz Y, Nikolaus S, Albrecht M, Hampe J, Lucius R, Klöppel G, Eickhoff H, Lehrach H, Lengauer T, Schreiber S. Costello CM, et al. Among authors: waetzig gh. PLoS Med. 2005 Aug;2(8):e199. doi: 10.1371/journal.pmed.0020199. Epub 2005 Aug 23. PLoS Med. 2005. PMID: 16107186 Free PMC article.
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways.
Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S. Rosenstiel P, et al. Among authors: waetzig gh. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3280-5. doi: 10.1073/pnas.0505423103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492792 Free PMC article.
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J. Rabe B, et al. Among authors: waetzig gh. Blood. 2008 Feb 1;111(3):1021-8. doi: 10.1182/blood-2007-07-102137. Epub 2007 Nov 7. Blood. 2008. PMID: 17989316 Free article.
N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.
Waetzig GH, Chalaris A, Rosenstiel P, Suthaus J, Holland C, Karl N, Vallés Uriarte L, Till A, Scheller J, Grötzinger J, Schreiber S, Rose-John S, Seegert D. Waetzig GH, et al. J Biol Chem. 2010 Jan 15;285(3):1781-9. doi: 10.1074/jbc.M109.075952. Epub 2009 Nov 13. J Biol Chem. 2010. PMID: 19915009 Free PMC article.
Essential role of neutrophil mobilization in concanavalin A-induced hepatitis is based on classic IL-6 signaling but not on IL-6 trans-signaling.
Malchow S, Thaiss W, Jänner N, Waetzig GH, Gewiese-Rabsch J, Garbers C, Yamamoto K, Rose-John S, Scheller J. Malchow S, et al. Among authors: waetzig gh. Biochim Biophys Acta. 2011 Mar;1812(3):290-301. doi: 10.1016/j.bbadis.2010.11.009. Epub 2010 Dec 2. Biochim Biophys Acta. 2011. PMID: 21130161 Free article.
52 results