Wagenaar FL - Search Results

1

Development of CCK-tetrapeptide analogues as potent and selective CCK-A receptor agonists.

Shiosaki K, Lin CW, Kopecka H, Craig R, Wagenaar FL, Bianchi B, Miller T, Witte D, Nadzan AM. Shiosaki K, et al. Among authors: wagenaar fl. J Med Chem. 1990 Nov;33(11):2950-2. doi: 10.1021/jm00173a006. J Med Chem. 1990. PMID: 1700123 No abstract available.

2

Cholecystokinin antagonists: (R)-tryptophan-based hybrid antagonists of high affinity and selectivity for CCK-A receptors.

Kerwin JF Jr, Wagenaar F, Kopecka H, Lin CW, Miller T, Witte D, Stashko M, Nadzan AM. Kerwin JF Jr, et al. J Med Chem. 1991 Dec;34(12):3350-9. doi: 10.1021/jm00116a002. J Med Chem. 1991. PMID: 1766000

3

Distinct requirements for activation at CCK-A and CCK-B/gastrin receptors: studies with a C-terminal hydrazide analogue of cholecystokinin tetrapeptide (30-33).

Lin CW, Holladay MW, Barrett RW, Wolfram CA, Miller TR, Witte D, Kerwin JF Jr, Wagenaar F, Nadzan AM. Lin CW, et al. Mol Pharmacol. 1989 Dec;36(6):881-6. Mol Pharmacol. 1989. PMID: 2601685

4

Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors.

Lin CW, Shiosaki K, Miller TR, Witte DG, Bianchi BR, Wolfram CA, Kopecka H, Craig R, Wagenaar F, Nadzan AM. Lin CW, et al. Mol Pharmacol. 1991 Mar;39(3):346-51. Mol Pharmacol. 1991. PMID: 1706470

5

Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.

Cowart M, Kowaluk EA, Daanen JF, Kohlhaas KL, Alexander KM, Wagenaar FL, Kerwin JF Jr. Cowart M, et al. Among authors: wagenaar fl. J Med Chem. 1998 Jul 2;41(14):2636-42. doi: 10.1021/jm980073h. J Med Chem. 1998. PMID: 9651169

6

Novel antibacterial class: a series of tetracyclic derivatives.

Hinman MM, Rosenberg TA, Balli D, Black-Schaefer C, Chovan LE, Kalvin D, Merta PJ, Nilius AM, Pratt SD, Soni NB, Wagenaar FL, Weitzberg M, Wagner R, Beutel BA. Hinman MM, et al. Among authors: wagenaar fl. J Med Chem. 2006 Aug 10;49(16):4842-56. doi: 10.1021/jm060010w. J Med Chem. 2006. PMID: 16884296

7

3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator.

Djuric SW, BaMaung NY, Basha A, Liu H, Luly JR, Madar DJ, Sciotti RJ, Tu NP, Wagenaar FL, Wiedeman PE, Zhou X, Ballaron S, Bauch J, Chen YW, Chiou XG, Fey T, Gauvin D, Gubbins E, Hsieh GC, Marsh KC, Mollison KW, Pong M, Shaughnessy TK, Sheets MP, Smith M, Trevillyan JM, Warrior U, Wegner CD, Carter GW. Djuric SW, et al. Among authors: wagenaar fl. J Med Chem. 2000 Aug 10;43(16):2975-81. doi: 10.1021/jm990615a. J Med Chem. 2000. PMID: 10956206

8

Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists.

Wang X, Kolasa T, El Kouhen OF, Chovan LE, Black-Shaefer CL, Wagenaar FL, Garton JA, Moreland RB, Honore P, Lau YY, Dandliker PJ, Brioni JD, Stewart AO. Wang X, et al. Among authors: wagenaar fl. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4303-7. doi: 10.1016/j.bmcl.2007.05.028. Epub 2007 May 16. Bioorg Med Chem Lett. 2007. PMID: 17532216

9

Nitric oxide synthase is critical in mediating basal forebrain regulation of cortical cerebral circulation.

Raszkiewicz JL, Linville DG, Kerwin JF Jr, Wagenaar F, Arneric SP. Raszkiewicz JL, et al. J Neurosci Res. 1992 Sep;33(1):129-35. doi: 10.1002/jnr.490330116. J Neurosci Res. 1992. PMID: 1280688

10

From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae.

Lerner CG, Hajduk PJ, Wagner R, Wagenaar FL, Woodall C, Gu YG, Searle XB, Florjancic AS, Zhang T, Clark RF, Cooper CS, Mack JC, Yu L, Cai M, Betz SF, Chovan LE, McCall JO, Black-Schaefer CL, Kakavas SJ, Schurdak ME, Comess KM, Walter KA, Edalji R, Dorwin SA, Smith RA, Hebert EJ, Harlan JE, Metzger RE, Merta PJ, Baranowski JL, Coen ML, Thornewell SJ, Shivakumar AG, Saiki AY, Soni N, Bui M, Balli DJ, Sanders WJ, Nilius AM, Holzman TF, Fesik SW, Beutel BA. Lerner CG, et al. Among authors: wagenaar fl. Chem Biol Drug Des. 2007 Jun;69(6):395-404. doi: 10.1111/j.1747-0285.2007.00521.x. Chem Biol Drug Des. 2007. PMID: 17581233

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