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PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background.
Glas J, Wagner J, Seiderer J, Olszak T, Wetzke M, Beigel F, Tillack C, Stallhofer J, Friedrich M, Steib C, Göke B, Ochsenkühn T, Karbalai N, Diegelmann J, Czamara D, Brand S. Glas J, et al. Among authors: wagner j. PLoS One. 2012;7(3):e33682. doi: 10.1371/journal.pone.0033682. Epub 2012 Mar 21. PLoS One. 2012. PMID: 22457781 Free PMC article.
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis.
Jürgens M, Laubender RP, Hartl F, Weidinger M, Seiderer J, Wagner J, Wetzke M, Beigel F, Pfennig S, Stallhofer J, Schnitzler F, Tillack C, Lohse P, Göke B, Glas J, Ochsenkühn T, Brand S. Jürgens M, et al. Among authors: wagner j. Am J Gastroenterol. 2010 Aug;105(8):1811-9. doi: 10.1038/ajg.2010.95. Epub 2010 Mar 2. Am J Gastroenterol. 2010. PMID: 20197757
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype.
Jürgens M, Brand S, Laubender RP, Seiderer J, Glas J, Wetzke M, Wagner J, Pfennig S, Tillack C, Beigel F, Weidinger M, Schnitzler F, Kreis ME, Göke B, Lohse P, Herrmann K, Ochsenkühn T. Jürgens M, et al. Among authors: wagner j. J Gastroenterol. 2010 Jul;45(7):721-31. doi: 10.1007/s00535-010-0231-7. Epub 2010 Apr 29. J Gastroenterol. 2010. PMID: 20428899
Analysis of IL12B gene variants in inflammatory bowel disease.
Glas J, Seiderer J, Wagner J, Olszak T, Fries C, Tillack C, Friedrich M, Beigel F, Stallhofer J, Steib C, Wetzke M, Göke B, Ochsenkühn T, Diegelmann J, Czamara D, Brand S. Glas J, et al. Among authors: wagner j. PLoS One. 2012;7(3):e34349. doi: 10.1371/journal.pone.0034349. Epub 2012 Mar 30. PLoS One. 2012. PMID: 22479607 Free PMC article.
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment.
Tillack C, Ehmann LM, Friedrich M, Laubender RP, Papay P, Vogelsang H, Stallhofer J, Beigel F, Bedynek A, Wetzke M, Maier H, Koburger M, Wagner J, Glas J, Diegelmann J, Koglin S, Dombrowski Y, Schauber J, Wollenberg A, Brand S. Tillack C, et al. Among authors: wagner j. Gut. 2014 Apr;63(4):567-77. doi: 10.1136/gutjnl-2012-302853. Epub 2013 Mar 6. Gut. 2014. PMID: 23468464
Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders.
Pavlou M, Schön C, Occelli LM, Rossi A, Meumann N, Boyd RF, Bartoe JT, Siedlecki J, Gerhardt MJ, Babutzka S, Bogedein J, Wagner JE, Priglinger SG, Biel M, Petersen-Jones SM, Büning H, Michalakis S. Pavlou M, et al. Among authors: wagner je. EMBO Mol Med. 2021 Apr 9;13(4):e13392. doi: 10.15252/emmm.202013392. Epub 2021 Feb 22. EMBO Mol Med. 2021. PMID: 33616280 Free PMC article.
A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation.
Böhm S, Splith V, Riedmayr LM, Rötzer RD, Gasparoni G, Nordström KJV, Wagner JE, Hinrichsmeyer KS, Walter J, Wahl-Schott C, Fenske S, Biel M, Michalakis S, Becirovic E. Böhm S, et al. Among authors: wagner je. Sci Adv. 2020 Aug 19;6(34):eaba5614. doi: 10.1126/sciadv.aba5614. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32875106 Free PMC article.
5,909 results