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Genetic instability, oncogenes, and the p53 pathway.
Wahl G, Vafa O. Wahl G, et al. Cold Spring Harb Symp Quant Biol. 2000;65:511-20. doi: 10.1101/sqb.2000.65.511. Cold Spring Harb Symp Quant Biol. 2000. PMID: 12760068 Review. No abstract available.
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.
Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, Furnari FB, Vandenberg SR, Rao PN, Wahl GM, Bafna V, Mischel PS. Turner KM, et al. Nature. 2017 Mar 2;543(7643):122-125. doi: 10.1038/nature21356. Epub 2017 Feb 8. Nature. 2017. PMID: 28178237 Free PMC article.
The p53 orchestra: Mdm2 and Mdmx set the tone.
Wade M, Wang YV, Wahl GM. Wade M, et al. Trends Cell Biol. 2010 May;20(5):299-309. doi: 10.1016/j.tcb.2010.01.009. Epub 2010 Feb 19. Trends Cell Biol. 2010. PMID: 20172729 Free PMC article. Review.
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