Chromosomal destabilization during gene amplification.
Ruiz JC, Wahl GM.
Ruiz JC, et al. Among authors: wahl gm.
Mol Cell Biol. 1990 Jun;10(6):3056-66. doi: 10.1128/mcb.10.6.3056-3066.1990.
Mol Cell Biol. 1990.
PMID: 2188107
Free PMC article.
The model system consists of a Chinese hamster cell line (L46) created by gene transfer in which the initial amplification product was shown previously to be an unstable extrachromosomal element containing an inverted duplication spanning more than 160 kilobases (J. C. Ruiz and …
The model system consists of a Chinese hamster cell line (L46) created by gene transfer in which the initial amplification product was shown …