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Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.
Rodríguez-Calvo R, Serrano L, Coll T, Moullan N, Sánchez RM, Merlos M, Palomer X, Laguna JC, Michalik L, Wahli W, Vázquez-Carrera M. Rodríguez-Calvo R, et al. Among authors: wahli w. Diabetes. 2008 Aug;57(8):2149-57. doi: 10.2337/db08-0176. Epub 2008 Apr 28. Diabetes. 2008. PMID: 18443198 Free PMC article.
Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.
Zarei M, Barroso E, Palomer X, Dai J, Rada P, Quesada-López T, Escolà-Gil JC, Cedó L, Zali MR, Molaei M, Dabiri R, Vázquez S, Pujol E, Valverde ÁM, Villarroya F, Liu Y, Wahli W, Vázquez-Carrera M. Zarei M, et al. Among authors: wahli w. Mol Metab. 2018 Feb;8:117-131. doi: 10.1016/j.molmet.2017.12.008. Epub 2017 Dec 19. Mol Metab. 2018. PMID: 29289645 Free PMC article.
Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes.
Zarei M, Barroso E, Palomer X, Escolà-Gil JC, Cedó L, Wahli W, Vázquez-Carrera M. Zarei M, et al. Among authors: wahli w. Clin Investig Arterioscler. 2019 May-Jun;31(3):111-118. doi: 10.1016/j.arteri.2019.01.004. Epub 2019 Apr 13. Clin Investig Arterioscler. 2019. PMID: 30987865 English, Spanish.
GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.
Aguilar-Recarte D, Barroso E, Gumà A, Pizarro-Delgado J, Peña L, Ruart M, Palomer X, Wahli W, Vázquez-Carrera M. Aguilar-Recarte D, et al. Among authors: wahli w. Cell Rep. 2021 Aug 10;36(6):109501. doi: 10.1016/j.celrep.2021.109501. Cell Rep. 2021. PMID: 34380027 Free article.
Knocking on GDF15's door for the treatment of type 2 diabetes mellitus.
Aguilar-Recarte D, Barroso E, Palomer X, Wahli W, Vázquez-Carrera M. Aguilar-Recarte D, et al. Among authors: wahli w. Trends Endocrinol Metab. 2022 Nov;33(11):741-754. doi: 10.1016/j.tem.2022.08.004. Epub 2022 Sep 20. Trends Endocrinol Metab. 2022. PMID: 36151002 Review.
340 results