Wai T - Search Results

1

Mitochondrial Dynamics and Metabolic Regulation.

Wai T, Langer T. Wai T, et al. Trends Endocrinol Metab. 2016 Feb;27(2):105-117. doi: 10.1016/j.tem.2015.12.001. Epub 2016 Jan 2. Trends Endocrinol Metab. 2016. PMID: 26754340 Review.

2

TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid.

Potting C, Tatsuta T, König T, Haag M, Wai T, Aaltonen MJ, Langer T. Potting C, et al. Among authors: wai t. Cell Metab. 2013 Aug 6;18(2):287-95. doi: 10.1016/j.cmet.2013.07.008. Cell Metab. 2013. PMID: 23931759

3

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.

Anand R, Wai T, Baker MJ, Kladt N, Schauss AC, Rugarli E, Langer T. Anand R, et al. Among authors: wai t. J Cell Biol. 2014 Mar 17;204(6):919-29. doi: 10.1083/jcb.201308006. Epub 2014 Mar 10. J Cell Biol. 2014. PMID: 24616225 Free PMC article.

4

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation.

Lagouge M, Mourier A, Lee HJ, Spåhr H, Wai T, Kukat C, Silva Ramos E, Motori E, Busch JD, Siira S; German Mouse Clinic Consortium, Kremmer E, Filipovska A, Larsson NG. Lagouge M, et al. Among authors: wai t. PLoS Genet. 2015 Aug 6;11(8):e1005423. doi: 10.1371/journal.pgen.1005423. eCollection 2015 Aug. PLoS Genet. 2015. PMID: 26247782 Free PMC article.

5

Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.

Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T. Sprenger HG, et al. Among authors: wai t. EMBO Mol Med. 2019 Jan;11(1):e9288. doi: 10.15252/emmm.201809288. EMBO Mol Med. 2019. PMID: 30389680 Free PMC article.

6

The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.

Wai T, Saita S, Nolte H, Müller S, König T, Richter-Dennerlein R, Sprenger HG, Madrenas J, Mühlmeister M, Brandt U, Krüger M, Langer T. Wai T, et al. EMBO Rep. 2016 Dec;17(12):1844-1856. doi: 10.15252/embr.201642698. Epub 2016 Oct 13. EMBO Rep. 2016. PMID: 27737933 Free PMC article.

7

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation.

Hartmann B, Wai T, Hu H, MacVicar T, Musante L, Fischer-Zirnsak B, Stenzel W, Gräf R, van den Heuvel L, Ropers HH, Wienker TF, Hübner C, Langer T, Kaindl AM. Hartmann B, et al. Among authors: wai t. Elife. 2016 Aug 6;5:e16078. doi: 10.7554/eLife.16078. Elife. 2016. PMID: 27495975 Free PMC article.

8

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice.

Wai T, García-Prieto J, Baker MJ, Merkwirth C, Benit P, Rustin P, Rupérez FJ, Barbas C, Ibañez B, Langer T. Wai T, et al. Science. 2015 Dec 4;350(6265):aad0116. doi: 10.1126/science.aad0116. Science. 2015. PMID: 26785494

9

Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function.

Mitsopoulos P, Chang YH, Wai T, König T, Dunn SD, Langer T, Madrenas J. Mitsopoulos P, et al. Among authors: wai t. Mol Cell Biol. 2015 May;35(10):1838-47. doi: 10.1128/MCB.00047-15. Epub 2015 Mar 16. Mol Cell Biol. 2015. PMID: 25776552 Free PMC article.

10

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission.

Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF. Freyer C, et al. Among authors: wai t. Nat Genet. 2012 Nov;44(11):1282-5. doi: 10.1038/ng.2427. Epub 2012 Oct 7. Nat Genet. 2012. PMID: 23042113 Free PMC article.

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