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Principles of antibody-mediated TNF receptor activation.
Wajant H. Wajant H. Cell Death Differ. 2015 Nov;22(11):1727-41. doi: 10.1038/cdd.2015.109. Epub 2015 Aug 21. Cell Death Differ. 2015. PMID: 26292758 Free PMC article. Review.
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor.
Grell M, Douni E, Wajant H, Löhden M, Clauss M, Maxeiner B, Georgopoulos S, Lesslauer W, Kollias G, Pfizenmaier K, Scheurich P. Grell M, et al. Among authors: wajant h. Cell. 1995 Dec 1;83(5):793-802. doi: 10.1016/0092-8674(95)90192-2. Cell. 1995. PMID: 8521496
Characterization of different soluble TNF receptor (TNFR80) derivatives: positive influence of the intracellular domain on receptor/ligand interaction and TNF neutralization capacity.
Moosmayer D, Wajant H, Gerlach E, Schmidt M, Brocks B, Pfizenmaier K. Moosmayer D, et al. Among authors: wajant h. J Interferon Cytokine Res. 1996 Jun;16(6):471-7. doi: 10.1089/jir.1996.16.471. J Interferon Cytokine Res. 1996. PMID: 8807502
Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site.
Weiss T, Grell M, Hessabi B, Bourteele S, Müller G, Scheurich P, Wajant H. Weiss T, et al. Among authors: wajant h. J Immunol. 1997 Mar 1;158(5):2398-404. J Immunol. 1997. PMID: 9036990
Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction.
Wajant H, Johannes FJ, Haas E, Siemienski K, Schwenzer R, Schubert G, Weiss T, Grell M, Scheurich P. Wajant H, et al. Curr Biol. 1998 Jan 15;8(2):113-6. doi: 10.1016/s0960-9822(98)70042-9. Curr Biol. 1998. PMID: 9427646
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor.
Grell M, Wajant H, Zimmermann G, Scheurich P. Grell M, et al. Among authors: wajant h. Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):570-5. doi: 10.1073/pnas.95.2.570. Proc Natl Acad Sci U S A. 1998. PMID: 9435233 Free PMC article.
Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1.
Grell M, Becke FM, Wajant H, Männel DN, Scheurich P. Grell M, et al. Among authors: wajant h. Eur J Immunol. 1998 Jan;28(1):257-63. doi: 10.1002/(SICI)1521-4141(199801)28:01<257::AID-IMMU257>3.0.CO;2-G. Eur J Immunol. 1998. PMID: 9485205
TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60.
Weiss T, Grell M, Siemienski K, Mühlenbeck F, Dürkop H, Pfizenmaier K, Scheurich P, Wajant H. Weiss T, et al. Among authors: wajant h. J Immunol. 1998 Sep 15;161(6):3136-42. J Immunol. 1998. PMID: 9743381
TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways.
Mühlenbeck F, Haas E, Schwenzer R, Schubert G, Grell M, Smith C, Scheurich P, Wajant H. Mühlenbeck F, et al. Among authors: wajant h. J Biol Chem. 1998 Dec 4;273(49):33091-8. doi: 10.1074/jbc.273.49.33091. J Biol Chem. 1998. PMID: 9830064
Identification of a TRAF (TNF receptor-associated factor) gene in Caenorhabditis elegans.
Wajant H, Mühlenbeck F, Scheurich P. Wajant H, et al. J Mol Evol. 1998 Dec;47(6):656-62. doi: 10.1007/pl00006423. J Mol Evol. 1998. PMID: 9847406
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