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Therapeutic targeting of CD70 and CD27.
Wajant H. Wajant H. Expert Opin Ther Targets. 2016 Aug;20(8):959-73. doi: 10.1517/14728222.2016.1158812. Epub 2016 Mar 15. Expert Opin Ther Targets. 2016. PMID: 26914723 Review.
Death receptors.
Wajant H. Wajant H. Essays Biochem. 2003;39:53-71. doi: 10.1042/bse0390053. Essays Biochem. 2003. PMID: 14585074 Review.
Analogies between Drosophila and mammalian TRAF pathways.
Wajant H, Scheurich P. Wajant H, et al. Prog Mol Subcell Biol. 2004;34:47-72. doi: 10.1007/978-3-642-18670-7_3. Prog Mol Subcell Biol. 2004. PMID: 14979664 Review.
TRAIL and NFkappaB signaling--a complex relationship.
Wajant H. Wajant H. Vitam Horm. 2004;67:101-32. doi: 10.1016/S0083-6729(04)67007-5. Vitam Horm. 2004. PMID: 15110174 Review.
Tumor therapeutics by design: targeting and activation of death receptors.
Wajant H, Gerspach J, Pfizenmaier K. Wajant H, et al. Cytokine Growth Factor Rev. 2005 Feb;16(1):55-76. doi: 10.1016/j.cytogfr.2004.12.001. Cytokine Growth Factor Rev. 2005. PMID: 15733832 Review.
Death receptor-induced signaling pathways are differentially regulated by gamma interferon upstream of caspase 8 processing.
Siegmund D, Wicovsky A, Schmitz I, Schulze-Osthoff K, Kreuz S, Leverkus M, Dittrich-Breiholz O, Kracht M, Wajant H. Siegmund D, et al. Mol Cell Biol. 2005 Aug;25(15):6363-79. doi: 10.1128/MCB.25.15.6363-6379.2005. Mol Cell Biol. 2005. PMID: 16024776 Free PMC article.
Interferons induce proteolytic degradation of TRAILR4.
Wicovsky A, Siegmund D, Wajant H. Wicovsky A, et al. Biochem Biophys Res Commun. 2005 Nov 11;337(1):184-90. doi: 10.1016/j.bbrc.2005.09.039. Biochem Biophys Res Commun. 2005. PMID: 16185657
CD95L/FasL and TRAIL in tumour surveillance and cancer therapy.
Wajant H. Wajant H. Cancer Treat Res. 2006;130:141-65. doi: 10.1007/0-387-26283-0_7. Cancer Treat Res. 2006. PMID: 16610707 Review.
Sustained JNK activation in response to tumor necrosis factor is mediated by caspases in a cell type-specific manner.
Wicovsky A, Müller N, Daryab N, Marienfeld R, Kneitz C, Kavuri S, Leverkus M, Baumann B, Wajant H. Wicovsky A, et al. J Biol Chem. 2007 Jan 26;282(4):2174-83. doi: 10.1074/jbc.M606167200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121845
Enforced covalent trimerization increases the activity of the TNF ligand family members TRAIL and CD95L.
Berg D, Lehne M, Müller N, Siegmund D, Münkel S, Sebald W, Pfizenmaier K, Wajant H. Berg D, et al. Cell Death Differ. 2007 Dec;14(12):2021-34. doi: 10.1038/sj.cdd.4402213. Epub 2007 Aug 17. Cell Death Differ. 2007. PMID: 17703232
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