Wakeham A - Search Results

1

Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development.

Reilly PT, Afzal S, Gorrini C, Lui K, Bukhman YV, Wakeham A, Haight J, Ling TW, Cheung CC, Elia AJ, Turner PV, Mak TW. Reilly PT, et al. Among authors: wakeham a. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10243-8. doi: 10.1073/pnas.1106211108. Epub 2011 Jun 2. Proc Natl Acad Sci U S A. 2011. PMID: 21636789 Free PMC article.

2

Brca2 is required for embryonic cellular proliferation in the mouse.

Suzuki A, de la Pompa JL, Hakem R, Elia A, Yoshida R, Mo R, Nishina H, Chuang T, Wakeham A, Itie A, Koo W, Billia P, Ho A, Fukumoto M, Hui CC, Mak TW. Suzuki A, et al. Among authors: wakeham a. Genes Dev. 1997 May 15;11(10):1242-52. doi: 10.1101/gad.11.10.1242. Genes Dev. 1997. PMID: 9171369 Free article.

3

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo.

Sirard C, de la Pompa JL, Elia A, Itie A, Mirtsos C, Cheung A, Hahn S, Wakeham A, Schwartz L, Kern SE, Rossant J, Mak TW. Sirard C, et al. Among authors: wakeham a. Genes Dev. 1998 Jan 1;12(1):107-19. doi: 10.1101/gad.12.1.107. Genes Dev. 1998. PMID: 9420335 Free PMC article.

4

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis.

Yeh WC, de la Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A, Ng M, Wakeham A, Khoo W, Mitchell K, El-Deiry WS, Lowe SW, Goeddel DV, Mak TW. Yeh WC, et al. Among authors: wakeham a. Science. 1998 Mar 20;279(5358):1954-8. doi: 10.1126/science.279.5358.1954. Science. 1998. PMID: 9506948

5

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum.

de la Pompa JL, Timmerman LA, Takimoto H, Yoshida H, Elia AJ, Samper E, Potter J, Wakeham A, Marengere L, Langille BL, Crabtree GR, Mak TW. de la Pompa JL, et al. Among authors: wakeham a. Nature. 1998 Mar 12;392(6672):182-6. doi: 10.1038/32419. Nature. 1998. PMID: 9515963

6

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice.

Suzuki A, de la Pompa JL, Stambolic V, Elia AJ, Sasaki T, del Barco Barrantes I, Ho A, Wakeham A, Itie A, Khoo W, Fukumoto M, Mak TW. Suzuki A, et al. Among authors: wakeham a. Curr Biol. 1998 Oct 22;8(21):1169-78. doi: 10.1016/s0960-9822(07)00488-5. Curr Biol. 1998. PMID: 9799734 Free article.

7

DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW. Hirao A, et al. Among authors: wakeham a. Science. 2000 Mar 10;287(5459):1824-7. doi: 10.1126/science.287.5459.1824. Science. 2000. PMID: 10710310

8

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice.

Rudolph D, Yeh WC, Wakeham A, Rudolph B, Nallainathan D, Potter J, Elia AJ, Mak TW. Rudolph D, et al. Among authors: wakeham a. Genes Dev. 2000 Apr 1;14(7):854-62. Genes Dev. 2000. PMID: 10766741 Free PMC article.

9

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development.

Yeh WC, Itie A, Elia AJ, Ng M, Shu HB, Wakeham A, Mirtsos C, Suzuki N, Bonnard M, Goeddel DV, Mak TW. Yeh WC, et al. Among authors: wakeham a. Immunity. 2000 Jun;12(6):633-42. doi: 10.1016/s1074-7613(00)80214-9. Immunity. 2000. PMID: 10894163 Free article.

10

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription.

Bonnard M, Mirtsos C, Suzuki S, Graham K, Huang J, Ng M, Itié A, Wakeham A, Shahinian A, Henzel WJ, Elia AJ, Shillinglaw W, Mak TW, Cao Z, Yeh WC. Bonnard M, et al. Among authors: wakeham a. EMBO J. 2000 Sep 15;19(18):4976-85. doi: 10.1093/emboj/19.18.4976. EMBO J. 2000. PMID: 10990461 Free PMC article.

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