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IL-11 is a crucial determinant of cardiovascular fibrosis.
Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, Tan J, Chothani SP, Ye L, Rackham OJL, Ko NSJ, Sahib NE, Pua CJ, Zhen NTG, Xie C, Wang M, Maatz H, Lim S, Saar K, Blachut S, Petretto E, Schmidt S, Putoczki T, Guimarães-Camboa N, Wakimoto H, van Heesch S, Sigmundsson K, Lim SL, Soon JL, Chao VTT, Chua YL, Tan TE, Evans SM, Loh YJ, Jamal MH, Ong KK, Chua KC, Ong BH, Chakaramakkil MJ, Seidman JG, Seidman CE, Hubner N, Sin KYK, Cook SA. Schafer S, et al. Among authors: wakimoto h. Nature. 2017 Dec 7;552(7683):110-115. doi: 10.1038/nature24676. Epub 2017 Nov 13. Nature. 2017. PMID: 29160304 Free PMC article.
Comparison of two murine models of familial hypertrophic cardiomyopathy.
McConnell BK, Fatkin D, Semsarian C, Jones KA, Georgakopoulos D, Maguire CT, Healey MJ, Mudd JO, Moskowitz IP, Conner DA, Giewat M, Wakimoto H, Berul CI, Schoen FJ, Kass DA, Seidman CE, Seidman JG. McConnell BK, et al. Among authors: wakimoto h. Circ Res. 2001 Mar 2;88(4):383-9. doi: 10.1161/01.res.88.4.383. Circ Res. 2001. PMID: 11230104
Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.
Wolf CM, Wang L, Alcalai R, Pizard A, Burgon PG, Ahmad F, Sherwood M, Branco DM, Wakimoto H, Fishman GI, See V, Stewart CL, Conner DA, Berul CI, Seidman CE, Seidman JG. Wolf CM, et al. Among authors: wakimoto h. J Mol Cell Cardiol. 2008 Feb;44(2):293-303. doi: 10.1016/j.yjmcc.2007.11.008. Epub 2007 Dec 3. J Mol Cell Cardiol. 2008. PMID: 18182166 Free PMC article.
Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation.
Alcalai R, Wakimoto H, Arad M, Planer D, Konno T, Wang L, Seidman JG, Seidman CE, Berul CI. Alcalai R, et al. Among authors: wakimoto h. J Cardiovasc Electrophysiol. 2011 Mar;22(3):316-24. doi: 10.1111/j.1540-8167.2010.01877.x. Epub 2010 Aug 30. J Cardiovasc Electrophysiol. 2011. PMID: 20807279 Free PMC article.
Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.
Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, Wakimoto H, Nayor M, Konno T, Gorham JM, Wolf CM, Kim JB, Schmitt JP, Molkentin JD, Norris RA, Tager AM, Hoffman SR, Markwald RR, Seidman CE, Seidman JG. Teekakirikul P, et al. Among authors: wakimoto h. J Clin Invest. 2010 Oct;120(10):3520-9. doi: 10.1172/JCI42028. Epub 2010 Sep 1. J Clin Invest. 2010. PMID: 20811150 Free PMC article.
Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.
Konno T, Chen D, Wang L, Wakimoto H, Teekakirikul P, Nayor M, Kawana M, Eminaga S, Gorham JM, Pandya K, Smithies O, Naya FJ, Olson EN, Seidman JG, Seidman CE. Konno T, et al. Among authors: wakimoto h. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18097-102. doi: 10.1073/pnas.1012826107. Epub 2010 Oct 5. Proc Natl Acad Sci U S A. 2010. PMID: 20923879 Free PMC article.
305 results