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Biochemistry and function of the DISC.
Walczak H, Sprick MR. Walczak H, et al. Trends Biochem Sci. 2001 Jul;26(7):452-3. doi: 10.1016/s0968-0004(01)01895-3. Trends Biochem Sci. 2001. PMID: 11440858 No abstract available.
Paving TRAIL's Path with Ubiquitin.
Lafont E, Hartwig T, Walczak H. Lafont E, et al. Trends Biochem Sci. 2018 Jan;43(1):44-60. doi: 10.1016/j.tibs.2017.11.002. Epub 2017 Nov 28. Trends Biochem Sci. 2018. PMID: 29195774 Review.
Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling.
Peltzer N, Darding M, Walczak H. Peltzer N, et al. Trends Cell Biol. 2016 Jun;26(6):445-461. doi: 10.1016/j.tcb.2016.01.006. Epub 2016 Feb 11. Trends Cell Biol. 2016. PMID: 26877205 Review.
Linear ubiquitination: a newly discovered regulator of cell signalling.
Rieser E, Cordier SM, Walczak H. Rieser E, et al. Trends Biochem Sci. 2013 Feb;38(2):94-102. doi: 10.1016/j.tibs.2012.11.007. Epub 2013 Jan 17. Trends Biochem Sci. 2013. PMID: 23333406 Review.
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.
Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T, Koschny R, Komander D, Silke J, Walczak H. Haas TL, et al. Mol Cell. 2009 Dec 11;36(5):831-44. doi: 10.1016/j.molcel.2009.10.013. Mol Cell. 2009. PMID: 20005846
The linear ubiquitin chain assembly complex forms part of the TNF-R1 signalling complex and is required for effective TNF-induced gene induction and prevents TNF-induced apoptosis.
Emmerich CH, Schmukle AC, Haas TL, Gerlach B, Cordier SM, Rieser E, Walczak H. Emmerich CH, et al. Adv Exp Med Biol. 2011;691:115-26. doi: 10.1007/978-1-4419-6612-4_12. Adv Exp Med Biol. 2011. PMID: 21153315 No abstract available.
Superantigen reactive Vbeta6+ T cells induce perforin/granzyme B mediated caspase-independent apoptosis in tumour cells.
Müerköster S, Weigand MA, Choi C, Walczak H, Schirrmacher V, Umansky V. Müerköster S, et al. Br J Cancer. 2002 Mar 4;86(5):828-36. doi: 10.1038/sj.bjc.6600104. Br J Cancer. 2002. PMID: 11875749 Free PMC article.
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2.
Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, Walczak H. Sprick MR, et al. Immunity. 2000 Jun;12(6):599-609. doi: 10.1016/s1074-7613(00)80211-3. Immunity. 2000. PMID: 10894160
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