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Does potency predict clinical efficacy? Illustration through an antihistamine model.
Waldman SA. Waldman SA. Ann Allergy Asthma Immunol. 2002 Jul;89(1):7-11; quiz 11-2, 77. doi: 10.1016/S1081-1206(10)61904-7. Ann Allergy Asthma Immunol. 2002. PMID: 12141724 Review.
First do no harm: managing antihistamine impairment in patients with allergic rhinitis.
Casale TB, Blaiss MS, Gelfand E, Gilmore T, Harvey PD, Hindmarch I, Simons FE, Spangler DL, Szefler SJ, Terndrup TE, Waldman SA, Weiler J, Wong DF; Antihistamine Impairment Roundtable. Casale TB, et al. J Allergy Clin Immunol. 2003 May;111(5):S835-42. doi: 10.1067/mai.2003.1550. J Allergy Clin Immunol. 2003. PMID: 12743547 Review.
Losartan does not affect the pharmacokinetics and pharmacodynamics of warfarin.
Kong AN, Tomasko L, Waldman SA, Osborne B, Deutsch PJ, Goldberg MR, Bjornsson TD. Kong AN, et al. J Clin Pharmacol. 1995 Oct;35(10):1008-15. doi: 10.1002/j.1552-4604.1995.tb04018.x. J Clin Pharmacol. 1995. PMID: 8568008 Clinical Trial.
Sensitivity in detecting drug-induced alterations in the PR interval: comparison of the surface electrocardiogram measured by a cardiologist versus routine automated computer analysis.
Morganroth J, Waldman SA. Morganroth J, et al. Am J Cardiol. 1993 Oct 1;72(11):834-6. doi: 10.1016/0002-9149(93)91076-t. Am J Cardiol. 1993. PMID: 8213522 No abstract available.
Hypotensive mechanisms of amifostine.
Ryan SV, Carrithers SL, Parkinson SJ, Skurk C, Nuss C, Pooler PM, Owen CS, Lefer AM, Waldman SA. Ryan SV, et al. J Clin Pharmacol. 1996 Apr;36(4):365-73. doi: 10.1002/j.1552-4604.1996.tb04214.x. J Clin Pharmacol. 1996. PMID: 8728352
Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.
Ruiz-Stewart I, Tiyyagura SR, Lin JE, Kazerounian S, Pitari GM, Schulz S, Martin E, Murad F, Waldman SA. Ruiz-Stewart I, et al. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):37-42. doi: 10.1073/pnas.0305080101. Epub 2003 Dec 18. Proc Natl Acad Sci U S A. 2004. PMID: 14684830 Free PMC article.
Regulation of nitric oxide-responsive recombinant soluble guanylyl cyclase by calcium.
Parkinson SJ, Jovanovic A, Jovanovic S, Wagner F, Terzic A, Waldman SA. Parkinson SJ, et al. Biochemistry. 1999 May 18;38(20):6441-8. doi: 10.1021/bi990154v. Biochemistry. 1999. PMID: 10350462
Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.
Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, Pitari GM. Lubbe WJ, et al. Clin Cancer Res. 2006 Mar 15;12(6):1876-82. doi: 10.1158/1078-0432.CCR-05-2686. Clin Cancer Res. 2006. PMID: 16551873
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