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p21 is necessary for the p53-mediated G1 arrest in human cancer cells.
Waldman T, Kinzler KW, Vogelstein B. Waldman T, et al. Cancer Res. 1995 Nov 15;55(22):5187-90. Cancer Res. 1995. PMID: 7585571
Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.
el-Deiry WS, Tokino T, Waldman T, Oliner JD, Velculescu VE, Burrell M, Hill DE, Healy E, Rees JL, Hamilton SR, et al. el-Deiry WS, et al. Cancer Res. 1995 Jul 1;55(13):2910-9. Cancer Res. 1995. PMID: 7796420
Repair Defect in p21 WAF1/CIP1 -/- human cancer cells.
McDonald ER 3rd, Wu GS, Waldman T, El-Deiry WS. McDonald ER 3rd, et al. Cancer Res. 1996 May 15;56(10):2250-5. Cancer Res. 1996. PMID: 8625293
Genetic determinants of p53-induced apoptosis and growth arrest.
Polyak K, Waldman T, He TC, Kinzler KW, Vogelstein B. Polyak K, et al. Genes Dev. 1996 Aug 1;10(15):1945-52. doi: 10.1101/gad.10.15.1945. Genes Dev. 1996. PMID: 8756351
Cell-cycle arrest versus cell death in cancer therapy.
Waldman T, Zhang Y, Dillehay L, Yu J, Kinzler K, Vogelstein B, Williams J. Waldman T, et al. Nat Med. 1997 Sep;3(9):1034-6. doi: 10.1038/nm0997-1034. Nat Med. 1997. PMID: 9288734
Requirement for p53 and p21 to sustain G2 arrest after DNA damage.
Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, Sedivy JM, Kinzler KW, Vogelstein B. Bunz F, et al. Science. 1998 Nov 20;282(5393):1497-501. doi: 10.1126/science.282.5393.1497. Science. 1998. PMID: 9822382
Disruption of p53 in human cancer cells alters the responses to therapeutic agents.
Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L, Williams J, Lengauer C, Kinzler KW, Vogelstein B. Bunz F, et al. J Clin Invest. 1999 Aug;104(3):263-9. doi: 10.1172/JCI6863. J Clin Invest. 1999. PMID: 10430607 Free PMC article.
A high-throughput screen with isogenic PTEN+/+ and PTEN-/- cells identifies CID1340132 as a novel compound that induces apoptosis in PTEN and PIK3CA mutant human cancer cells.
Li HF, Keeton A, Vitolo M, Maddox C, Rasmussen L, Hobrath J, White EL, Park BH, Piazza GA, Kim JS, Waldman T. Li HF, et al. J Biomol Screen. 2011 Apr;16(4):383-93. doi: 10.1177/1087057110397357. Epub 2011 Feb 18. J Biomol Screen. 2011. PMID: 21335596 Free PMC article.
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