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Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma.
Yang Y, Shaffer AL 3rd, Emre NC, Ceribelli M, Zhang M, Wright G, Xiao W, Powell J, Platig J, Kohlhammer H, Young RM, Zhao H, Yang Y, Xu W, Buggy JJ, Balasubramanian S, Mathews LA, Shinn P, Guha R, Ferrer M, Thomas C, Waldmann TA, Staudt LM. Yang Y, et al. Among authors: Waldmann TA. Cancer Cell. 2012 Jun 12;21(6):723-37. doi: 10.1016/j.ccr.2012.05.024. Cancer Cell. 2012. PMID: 22698399 Free PMC article.
Deletion of the p16INK4A gene in ex vivo acute adult T cell lymphoma/leukemia cells and methylation of the p16INK4A promoter in HTLV type I-infected T cell lines.
Trovato R, Cereseto A, Takemoto S, Gessain A, Watanabe T, Waldmann T, Franchini G. Trovato R, et al. Among authors: Waldmann T. AIDS Res Hum Retroviruses. 2000 May 20;16(8):709-13. doi: 10.1089/088922200308701. AIDS Res Hum Retroviruses. 2000. PMID: 10826477
Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins.
Takemoto S, Mulloy JC, Cereseto A, Migone TS, Patel BK, Matsuoka M, Yamaguchi K, Takatsuki K, Kamihira S, White JD, Leonard WJ, Waldmann T, Franchini G. Takemoto S, et al. Among authors: Waldmann T. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13897-902. doi: 10.1073/pnas.94.25.13897. Proc Natl Acad Sci U S A. 1997. PMID: 9391124 Free PMC article.
The combination of zidovudine and interferon alpha-2B in the treatment of adult T-cell leukemia/lymphoma.
White JD, Wharfe G, Stewart DM, Maher VE, Eicher D, Herring B, Derby M, Jackson-Booth PG, Marshall M, Lucy D, Jain A, Cranston B, Hanchard B, Lee CC, Top LE, Fleisher TA, Nelson DL, Waldmann TA. White JD, et al. Among authors: Waldmann TA. Leuk Lymphoma. 2001 Jan;40(3-4):287-94. doi: 10.3109/10428190109057927. Leuk Lymphoma. 2001. PMID: 11426550 Clinical Trial.
Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas.
Nicolae A, Xi L, Pittaluga S, Abdullaev Z, Pack SD, Chen J, Waldmann TA, Jaffe ES, Raffeld M. Nicolae A, et al. Among authors: Waldmann TA. Leukemia. 2014 Nov;28(11):2244-8. doi: 10.1038/leu.2014.200. Epub 2014 Jun 20. Leukemia. 2014. PMID: 24947020 No abstract available.
Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model.
Yu P, Petrus MN, Ju W, Zhang M, Conlon KC, Nakagawa M, Maeda M, Bamford RN, Waldmann TA. Yu P, et al. Among authors: Waldmann TA. Leukemia. 2015 Mar;29(3):556-66. doi: 10.1038/leu.2014.241. Epub 2014 Aug 14. Leukemia. 2015. PMID: 25118879 Free PMC article.
Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: antiproliferative activity on human breast carcinoma cell lines.
Mandler R, Wu C, Sausville EA, Roettinger AJ, Newman DJ, Ho DK, King CR, Yang D, Lippman ME, Landolfi NF, Dadachova E, Brechbiel MW, Waldmann TA. Mandler R, et al. Among authors: Waldmann TA. J Natl Cancer Inst. 2000 Oct 4;92(19):1573-81. doi: 10.1093/jnci/92.19.1573. J Natl Cancer Inst. 2000. PMID: 11018093
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