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Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.
Mitra S, Ring AM, Amarnath S, Spangler JB, Li P, Ju W, Fischer S, Oh J, Spolski R, Weiskopf K, Kohrt H, Foley JE, Rajagopalan S, Long EO, Fowler DH, Waldmann TA, Garcia KC, Leonard WJ. Mitra S, et al. Among authors: waldmann ta. Immunity. 2015 May 19;42(5):826-38. doi: 10.1016/j.immuni.2015.04.018. Immunity. 2015. PMID: 25992859 Free PMC article.
The interleukin-2 receptor.
Waldmann TA. Waldmann TA. J Biol Chem. 1991 Feb 15;266(5):2681-4. J Biol Chem. 1991. PMID: 1993646 Free article. Review. No abstract available.
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC. Depper JM, et al. Among authors: waldmann ta. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4230-4. doi: 10.1073/pnas.82.12.4230. Proc Natl Acad Sci U S A. 1985. PMID: 2987968 Free PMC article.
654 results