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Stereoisomers of ketoconazole: preparation and biological activity.
Rotstein DM, Kertesz DJ, Walker KA, Swinney DC. Rotstein DM, et al. J Med Chem. 1992 Jul 24;35(15):2818-25. doi: 10.1021/jm00093a015. J Med Chem. 1992. PMID: 1495014
Lactams as EP4 prostanoid receptor agonists. 3. Discovery of N-ethylbenzoic acid 2-pyrrolidinones as subtype selective agents.
Elworthy TR, Brill ER, Chiou SS, Chu F, Harris JR, Hendricks RT, Huang J, Kim W, Lach LK, Mirzadegan T, Yee C, Walker KA. Elworthy TR, et al. J Med Chem. 2004 Dec 2;47(25):6124-7. doi: 10.1021/jm049290a. J Med Chem. 2004. PMID: 15566283
Rational design of 6-methylsulfonylindoles as selective cyclooxygenase-2 inhibitors.
Campbell JA, Bordunov V, Broka CA, Browner MF, Kress JM, Mirzadegan T, Ramesha C, Sanpablo BF, Stabler R, Takahara P, Villasenor A, Walker KA, Wang JH, Welch M, Weller P. Campbell JA, et al. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4741-5. doi: 10.1016/j.bmcl.2004.06.075. Bioorg Med Chem Lett. 2004. PMID: 15324899
Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase. Part 2: Solid-phase optimization of side chains.
Dankwardt SM, Abbot SC, Broka CA, Martin RL, Chan CS, Springman EB, Van Wart HE, Walker KA. Dankwardt SM, et al. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1233-5. doi: 10.1016/s0960-894x(02)00117-8. Bioorg Med Chem Lett. 2002. PMID: 11934595
Design and synthesis of orally active inhibitors of TNF synthesis as anti-rheumatoid arthritis drugs.
Chen JJ, Dewdney N, Lin X, Martin RL, Walker KA, Huang J, Chu F, Eugui E, Mirkovich A, Kim Y, Sarma K, Arzeno H, Van Wart HE. Chen JJ, et al. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3951-4. doi: 10.1016/j.bmcl.2003.08.076. Bioorg Med Chem Lett. 2003. PMID: 14592482
1-(4-Aminobenzyl)-and 1-(4-aminophenyl)isoquinoline derivatives: synthesis and evaluation as potential irreversible cyclic nucleotide phosphodiesterase inhibitors.
Walker KA, Boots MR, Stubbins JF, Rogers ME, Davis CW. Walker KA, et al. J Med Chem. 1983 Feb;26(2):174-81. doi: 10.1021/jm00356a011. J Med Chem. 1983. PMID: 6298424
Antitrichomonal activity of mesoionic thiazolo[3,2-a]pyridines.
Walker KA, Sjogren EB, Matthews TR. Walker KA, et al. J Med Chem. 1985 Nov;28(11):1673-9. doi: 10.1021/jm00149a023. J Med Chem. 1985. PMID: 4067993
Monomethyl ether derivatives of 7,8-dihydroxy- and 8,9-dihydroxy-4-n-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines as possible products of metabolism by catechol-O-methyltransferase.
Cannon JG, Walker KA, Montanari A, Long JP, Flynn JR. Cannon JG, et al. J Med Chem. 1990 Jul;33(7):2000-6. doi: 10.1021/jm00169a031. J Med Chem. 1990. PMID: 2362281
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