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Chronic obstructive pulmonary disease.
Calverley PM, Walker P. Calverley PM, et al. Lancet. 2003 Sep 27;362(9389):1053-61. doi: 10.1016/s0140-6736(03)14416-9. Lancet. 2003. PMID: 14522537 Review.
Upper airways abnormalities and tracheal problems in Morquio's disease.
Walker PP, Rose E, Williams JG. Walker PP, et al. Thorax. 2003 May;58(5):458-9. doi: 10.1136/thorax.58.5.458. Thorax. 2003. PMID: 12728175 Free PMC article.
Intravenous aminophylline in patients admitted to hospital with non-acidotic exacerbations of chronic obstructive pulmonary disease: a prospective randomised controlled trial.
Duffy N, Walker P, Diamantea F, Calverley PM, Davies L. Duffy N, et al. Thorax. 2005 Sep;60(9):713-7. doi: 10.1136/thx.2004.036046. Epub 2005 Jun 6. Thorax. 2005. PMID: 15939732 Free PMC article. Clinical Trial.
In the aminophylline group, 2 hours of treatment produced a small but significant rise in arterial pH (p = 0.001) and a fall in arterial carbon dioxide tension (p = 0.01) compared with placebo treatment. ...Nausea was a more frequent side effect in the aminophylline …
In the aminophylline group, 2 hours of treatment produced a small but significant rise in arterial pH (p = 0.001) and a fall in arter …
Lung mechanics and dyspnea during exacerbations of chronic obstructive pulmonary disease.
Stevenson NJ, Walker PP, Costello RW, Calverley PM. Stevenson NJ, et al. Am J Respir Crit Care Med. 2005 Dec 15;172(12):1510-6. doi: 10.1164/rccm.200504-595OC. Epub 2005 Sep 15. Am J Respir Crit Care Med. 2005. PMID: 16166620
MAIN RESULTS: Postbronchodilator inspiratory capacity increased 0.23 +/- 0.07 L by discharge and 0.42 +/- 0.1 L by Day 42, FEV1 rose 0.09 +/- 0.04 and 0.2 +/- 0.05 L at discharge and Day 42, respectively, and FVC increased 0.21 +/- 0.08 and 0.47 +/- 0.09 L at discharge and Day 42 …
MAIN RESULTS: Postbronchodilator inspiratory capacity increased 0.23 +/- 0.07 L by discharge and 0.42 +/- 0.1 L by Day 42, FEV1 rose 0.09 +/ …
COPD exacerbations. 4: Prevention.
Scott S, Walker P, Calverley PM. Scott S, et al. Thorax. 2006 May;61(5):440-7. doi: 10.1136/thx.2005.041848. Thorax. 2006. PMID: 16648352 Free PMC article. Review.
Effect of primary-care spirometry on the diagnosis and management of COPD.
Walker PP, Mitchell P, Diamantea F, Warburton CJ, Davies L. Walker PP, et al. Eur Respir J. 2006 Nov;28(5):945-52. doi: 10.1183/09031936.06.00019306. Epub 2006 Jul 26. Eur Respir J. 2006. PMID: 16870668
Lower limb activity and its determinants in COPD.
Walker PP, Burnett A, Flavahan PW, Calverley PM. Walker PP, et al. Thorax. 2008 Aug;63(8):683-9. doi: 10.1136/thx.2007.087130. Epub 2008 May 16. Thorax. 2008. PMID: 18487318
Mean leg activity, mean intensity of leg activity and the time that patients spent mobile at home were all related to forced expiratory volume in 1 s (FEV(1)) (r = 0.57, p = 0.001; r = 0.5, p = 0.003; and r = 0.51, p = 0.002, respectively), but intensity of a …
Mean leg activity, mean intensity of leg activity and the time that patients spent mobile at home were all related to forced expiratory volu …
The volumetric response to bronchodilators in stable chronic obstructive pulmonary disease.
Walker PP, Calverley PM. Walker PP, et al. COPD. 2008 Jun;5(3):147-52. doi: 10.1080/15412550802092928. COPD. 2008. PMID: 18568838

These 'volume responders' had greater degrees of airflow obstruction-lower FEV(1) (p < 0.001) and FEV(1)/FVC (p < 0.05)-and a higher residual volume at rest (p = 0.005) with similar degrees of emphysema measured by K(CO). Subjects with evidence of great

These 'volume responders' had greater degrees of airflow obstruction-lower FEV(1) (p < 0.001) and FEV(1)/FVC (p < 0.05)-

Lung function changes following methacholine inhalation in COPD.
Walker PP, Hadcroft J, Costello RW, Calverley PM. Walker PP, et al. Respir Med. 2009 Apr;103(4):535-41. doi: 10.1016/j.rmed.2008.11.002. Epub 2008 Dec 10. Respir Med. 2009. PMID: 19081234
Comparing baseline to PC(20) there were significant falls in forced vital capacity (FVC) (2.91 vs. 2.2L; p<0.001), slow vital capacity (3.22 vs. 2.58L; p<0.001) and IC (2.21 vs. 1.75L; p<0.001) without change in FEV(1)/FVC ratio (0.52 vs. 0.52; not s …
Comparing baseline to PC(20) there were significant falls in forced vital capacity (FVC) (2.91 vs. 2.2L; p<0.001), slow vital capa …
Reducing exacerbations in patients with COPD.
Walker P, Ashish A. Walker P, et al. Practitioner. 2008 Nov;252(1712):16, 18, 20 passim. Practitioner. 2008. PMID: 19130718 No abstract available.
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