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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.
Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D. Woods A, et al. Among authors: wallimann t. Curr Biol. 2003 Nov 11;13(22):2004-8. doi: 10.1016/j.cub.2003.10.031. Curr Biol. 2003. PMID: 14614828 Free article.
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.
Horman S, Vertommen D, Heath R, Neumann D, Mouton V, Woods A, Schlattner U, Wallimann T, Carling D, Hue L, Rider MH. Horman S, et al. Among authors: wallimann t. J Biol Chem. 2006 Mar 3;281(9):5335-40. doi: 10.1074/jbc.M506850200. Epub 2005 Dec 9. J Biol Chem. 2006. PMID: 16340011 Free article.
Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding.
Riek U, Scholz R, Konarev P, Rufer A, Suter M, Nazabal A, Ringler P, Chami M, Müller SA, Neumann D, Forstner M, Hennig M, Zenobi R, Engel A, Svergun D, Schlattner U, Wallimann T. Riek U, et al. Among authors: wallimann t. J Biol Chem. 2008 Jun 27;283(26):18331-43. doi: 10.1074/jbc.M708379200. Epub 2008 Mar 27. J Biol Chem. 2008. PMID: 18372250 Free article.
258 results