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Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A.
Walsh AH, Cheng A, Honkanen RE. Walsh AH, et al. FEBS Lett. 1997 Oct 27;416(3):230-4. doi: 10.1016/s0014-5793(97)01210-6. FEBS Lett. 1997. PMID: 9373158 Free article.
Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia.
Weinbrenner C, Baines CP, Liu GS, Armstrong SC, Ganote CE, Walsh AH, Honkanen RE, Cohen MV, Downey JM. Weinbrenner C, et al. Among authors: walsh ah. Circulation. 1998 Sep 1;98(9):899-905. doi: 10.1161/01.cir.98.9.899. Circulation. 1998. PMID: 9738645
Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity.
Cheng A, Balczon R, Zuo Z, Koons JS, Walsh AH, Honkanen RE. Cheng A, et al. Among authors: walsh ah. Cancer Res. 1998 Aug 15;58(16):3611-9. Cancer Res. 1998. PMID: 9721869 Free article.
Model development and analysis of tenidap-induced proteinuria in the rat.
Aleo MD, Wang T, Giebisch G, Sanders MJ, Walsh AH, Lopez-Anaya A. Aleo MD, et al. Among authors: walsh ah. J Pharmacol Exp Ther. 1996 Dec;279(3):1318-26. J Pharmacol Exp Ther. 1996. PMID: 8968356
Skeletal lesions and deformities in large sharks.
Hoenig JM, Walsh AH. Hoenig JM, et al. Among authors: walsh ah. J Wildl Dis. 1983 Jan;19(1):27-33. doi: 10.7589/0090-3558-19.1.27. J Wildl Dis. 1983. PMID: 6842732
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