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Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG. Yin H, et al. Nat Biotechnol. 2017 Dec;35(12):1179-1187. doi: 10.1038/nbt.4005. Epub 2017 Nov 13. Nat Biotechnol. 2017. PMID: 29131148 Free PMC article.
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo.
Yin H, Song CQ, Dorkin JR, Zhu LJ, Li Y, Wu Q, Park A, Yang J, Suresh S, Bizhanova A, Gupta A, Bolukbasi MF, Walsh S, Bogorad RL, Gao G, Weng Z, Dong Y, Koteliansky V, Wolfe SA, Langer R, Xue W, Anderson DG. Yin H, et al. Nat Biotechnol. 2016 Mar;34(3):328-33. doi: 10.1038/nbt.3471. Epub 2016 Feb 1. Nat Biotechnol. 2016. PMID: 26829318 Free PMC article.
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.
Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG. Yin H, et al. Nat Chem Biol. 2018 Mar;14(3):311-316. doi: 10.1038/nchembio.2559. Epub 2018 Jan 29. Nat Chem Biol. 2018. PMID: 29377001 Free PMC article.
Disaster plant pathology: Smart solutions for threats to global plant health from natural and human-driven disasters.
Etherton BA, Choudhury RA, Alcalá Briseño RI, Mouafo-Tchinda RA, Plex Sulá AI, Choudhary M, Adhikari A, Lei SL, Kraisitudomsook N, Robledo Buritica J, Cerbaro VA, Ogero K, Cox CM, Walsh SP, Andrade-Piedra J, Omondi BA, Navarrete I, McEwan MA, Garrett KA. Etherton BA, et al. Among authors: walsh sp. Phytopathology. 2024 Apr 9. doi: 10.1094/PHYTO-03-24-0079-FI. Online ahead of print. Phytopathology. 2024. PMID: 38593748
Neuroinflammation: Breaking barriers and bridging gaps.
Estera LA, Walsh SP, Headen JA, Williamson RE, Kalinski AL. Estera LA, et al. Among authors: walsh sp. Neurosci Res. 2023 Dec;197:9-17. doi: 10.1016/j.neures.2021.11.001. Epub 2021 Nov 6. Neurosci Res. 2023. PMID: 34748905 Review.
Estimate your dose: RADDOSE-3D.
Bury CS, Brooks-Bartlett JC, Walsh SP, Garman EF. Bury CS, et al. Among authors: walsh sp. Protein Sci. 2018 Jan;27(1):217-228. doi: 10.1002/pro.3302. Epub 2017 Nov 6. Protein Sci. 2018. PMID: 28921782 Free PMC article.
44 results