Wan Y - Search Results

1

Comparing the relative robustness of anion exchange and the corresponding mixed-mode chromatography on removing a weakly-bound byproduct: A case study of bispecific antibody purification.

Zhang S, Zhang T, Li Y, Wan Y. Zhang S, et al. Among authors: wan y. Protein Expr Purif. 2021 Nov;187:105948. doi: 10.1016/j.pep.2021.105948. Epub 2021 Jul 22. Protein Expr Purif. 2021. PMID: 34303809

2

Sodium caprylate induced precipitation post Protein A chromatography as an effective means for host cell protein clearance.

Wan Y, Zhang T, Chen T, Wang Y, Li Y. Wan Y, et al. Protein Expr Purif. 2019 Dec;164:105460. doi: 10.1016/j.pep.2019.105460. Epub 2019 Jul 25. Protein Expr Purif. 2019. PMID: 31351123

3

Removing light chain-missing byproducts and aggregates by Capto MMC ImpRes mixed-mode chromatography during the purification of two WuXiBody-based bispecific antibodies.

Wan Y, Zhang T, Wang Y, Wang Y, Li Y. Wan Y, et al. Protein Expr Purif. 2020 Nov;175:105712. doi: 10.1016/j.pep.2020.105712. Epub 2020 Jul 29. Protein Expr Purif. 2020. PMID: 32738441

4

Comparing the relative robustness of byproduct removal by wash and by elution in column chromatography for the purification of a bispecific antibody.

Wan Y, Zhang T, Wang Y, Li Y. Wan Y, et al. Protein Expr Purif. 2021 Jan;177:105762. doi: 10.1016/j.pep.2020.105762. Epub 2020 Sep 21. Protein Expr Purif. 2021. PMID: 32971297

5

Application of pH-salt dual gradient elution in purifying a WuXiBody-based bispecific antibody by MMC ImpRes mixed-mode chromatography.

Wan Y, Wang Y, Zhang T, Zhang S, Wang Y, Li Y. Wan Y, et al. Protein Expr Purif. 2021 May;181:105822. doi: 10.1016/j.pep.2021.105822. Epub 2021 Jan 9. Protein Expr Purif. 2021. PMID: 33429037

6

Removing a single-arm species by Fibro PrismA in purifying an asymmetric IgG-like bispecific antibody.

Zhang T, Wan Y, Wang Y, Li Y. Zhang T, et al. Among authors: wan y. Protein Expr Purif. 2021 Jun;182:105847. doi: 10.1016/j.pep.2021.105847. Epub 2021 Feb 13. Protein Expr Purif. 2021. PMID: 33588033

7

Removing a light-chain missing byproduct by MMC ImpRes mixed-mode chromatography under weak partitioning mode in purifying a WuXiBody-based bispecific antibody.

Zhang T, Wan Y, Duan J, Li Y. Zhang T, et al. Among authors: wan y. Protein Expr Purif. 2021 Oct;186:105927. doi: 10.1016/j.pep.2021.105927. Epub 2021 Jun 8. Protein Expr Purif. 2021. PMID: 34111551

8

Evaluating a new mixed-mode resin Diamond MMC Mustang using Capto MMC ImpRes as a benchmark.

Zhang S, Wan Y, Duan J, Li Y. Zhang S, et al. Among authors: wan y. Protein Expr Purif. 2021 Oct;186:105930. doi: 10.1016/j.pep.2021.105930. Epub 2021 Jun 18. Protein Expr Purif. 2021. PMID: 34147604

9

Assessing four subdomain-specific affinity resins' capability to separate half-antibody from intact bispecific antibody.

Chen W, Zhang T, Wan Y, Li Y. Chen W, et al. Among authors: wan y. Protein Expr Purif. 2022 Oct;198:106124. doi: 10.1016/j.pep.2022.106124. Epub 2022 May 31. Protein Expr Purif. 2022. PMID: 35661701

10

Screening of six cation exchange resins for high binding capacity, monomer purity and step yield: A case study.

Lu W, Zhang Z, Zhang S, Zhang T, Wan Y, Li Y. Lu W, et al. Among authors: wan y. Protein Expr Purif. 2022 Nov;199:106155. doi: 10.1016/j.pep.2022.106155. Epub 2022 Aug 12. Protein Expr Purif. 2022. PMID: 35970491

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