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Radiolabeled cyclic RGD peptides as radiotracers for tumor imaging.
Shi J, Wang F, Liu S. Shi J, et al. Among authors: wang f. Biophys Rep. 2016;2(1):1-20. doi: 10.1007/s41048-016-0021-8. Epub 2016 Apr 12. Biophys Rep. 2016. PMID: 27819026 Free PMC article. Review.
99mTc-labeled cyclic RGDfK dimer: initial evaluation for SPECT imaging of glioma integrin alphavbeta3 expression.
Jia B, Shi J, Yang Z, Xu B, Liu Z, Zhao H, Liu S, Wang F. Jia B, et al. Among authors: wang f. Bioconjug Chem. 2006 Jul-Aug;17(4):1069-76. doi: 10.1021/bc060055b. Bioconjug Chem. 2006. PMID: 16848417
Evaluation of a (99m)Tc-labeled cyclic RGD tetramer for noninvasive imaging integrin alpha(v)beta3-positive breast cancer.
Liu S, Hsieh WY, Jiang Y, Kim YS, Sreerama SG, Chen X, Jia B, Wang F. Liu S, et al. Among authors: wang f. Bioconjug Chem. 2007 Mar-Apr;18(2):438-46. doi: 10.1021/bc0603081. Epub 2007 Mar 7. Bioconjug Chem. 2007. PMID: 17341108
Linker effects on biological properties of 111In-labeled DTPA conjugates of a cyclic RGDfK dimer.
Jia B, Liu Z, Shi J, Yu Z, Yang Z, Zhao H, He Z, Liu S, Wang F. Jia B, et al. Among authors: wang f. Bioconjug Chem. 2008 Jan;19(1):201-10. doi: 10.1021/bc7002988. Epub 2007 Dec 11. Bioconjug Chem. 2008. PMID: 18069778 Free PMC article.
99mTc-labeled bombesin(7-14)NH2 with favorable properties for SPECT imaging of colon cancer.
Shi J, Jia B, Liu Z, Yang Z, Yu Z, Chen K, Chen X, Liu S, Wang F. Shi J, et al. Among authors: wang f. Bioconjug Chem. 2008 Jun;19(6):1170-8. doi: 10.1021/bc700471z. Epub 2008 May 21. Bioconjug Chem. 2008. PMID: 18491928
Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers.
Wang L, Shi J, Kim YS, Zhai S, Jia B, Zhao H, Liu Z, Wang F, Chen X, Liu S. Wang L, et al. Among authors: wang f. Mol Pharm. 2009 Jan-Feb;6(1):231-45. doi: 10.1021/mp800150r. Mol Pharm. 2009. PMID: 19067525 Free PMC article.
Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using 18F-labeled PEGylated RGD-bombesin heterodimer 18F-FB-PEG3-Glu-RGD-BBN.
Liu Z, Yan Y, Chin FT, Wang F, Chen X. Liu Z, et al. Among authors: wang f. J Med Chem. 2009 Jan 22;52(2):425-32. doi: 10.1021/jm801285t. J Med Chem. 2009. PMID: 19113865
A PEG(3) spacer was attached to the glutamate alpha-amino group of Glu-RGD-BBN to enhance the (18)F labeling yield and to improve the in vivo kinetics. ...The dual-receptor targeting properties of (18)F-FB-PEG(3)-Glu-RGD-BBN were observed in PC-3 tumor model. (18) …
A PEG(3) spacer was attached to the glutamate alpha-amino group of Glu-RGD-BBN to enhance the (18)F labeling yield and to improve the …
(68)Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin alphavbeta3 PET imaging.
Liu Z, Niu G, Shi J, Liu S, Wang F, Liu S, Chen X. Liu Z, et al. Among authors: wang f. Eur J Nucl Med Mol Imaging. 2009 Jun;36(6):947-57. doi: 10.1007/s00259-008-1045-1. Epub 2009 Jan 22. Eur J Nucl Med Mol Imaging. 2009. PMID: 19159928
PURPOSE: Radiolabeled cyclic RGD (Arg-Gly-Asp) peptides have great potential for the early tumor detection and noninvasive monitoring of tumor metastasis and therapeutic response. (18)F-labeled RGD analogs ([(18)F]-AH111585 and [(18)F]Galacto-RGD) have been i …
PURPOSE: Radiolabeled cyclic RGD (Arg-Gly-Asp) peptides have great potential for the early tumor detection and noninvasive monitoring of tum …
Noninvasive imaging of tumor integrin expression using (18)F-labeled RGD dimer peptide with PEG (4) linkers.
Liu Z, Liu S, Wang F, Liu S, Chen X. Liu Z, et al. Among authors: wang f. Eur J Nucl Med Mol Imaging. 2009 Aug;36(8):1296-307. doi: 10.1007/s00259-009-1112-2. Epub 2009 Mar 19. Eur J Nucl Med Mol Imaging. 2009. PMID: 19296102
METHODS: P-PRGD2 was labeled with (18)F via 4-nitrophenyl 2-(18)F-fluoropropionate ((18)F-FP) prosthetic group. In vitro and in vivo characteristics of the new dimeric RGD peptide tracer (18)F-FP-P-PRGD2 were investigated and compared with those of (18 …
METHODS: P-PRGD2 was labeled with (18)F via 4-nitrophenyl 2-(18)F-fluoropropionate ((18)F-FP) prosthetic group. In vitr …
99mTcO(MAG2-3G3-dimer): a new integrin alpha(v)beta(3)-targeted SPECT radiotracer with high tumor uptake and favorable pharmacokinetics.
Shi J, Wang L, Kim YS, Zhai S, Jia B, Wang F, Liu S. Shi J, et al. Among authors: wang l, wang f. Eur J Nucl Med Mol Imaging. 2009 Nov;36(11):1874-84. doi: 10.1007/s00259-009-1166-1. Epub 2009 May 30. Eur J Nucl Med Mol Imaging. 2009. PMID: 19484236
CONCLUSION: (99m)TcO(MAG(2)-3G(3)-dimer) is a very attractive radiotracer for early detection of integrin alpha(v)beta(3)-positive tumors and has significant advantages over the (18)F-labeled RGD peptide radiotracers with respect to the cost, availability, and easiness for …
CONCLUSION: (99m)TcO(MAG(2)-3G(3)-dimer) is a very attractive radiotracer for early detection of integrin alpha(v)beta(3)-positive tumors an …
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