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Unspliced X-box-binding protein 1 (XBP1) protects endothelial cells from oxidative stress through interaction with histone deacetylase 3.
Martin D, Li Y, Yang J, Wang G, Margariti A, Jiang Z, Yu H, Zampetaki A, Hu Y, Xu Q, Zeng L. Martin D, et al. Among authors: Wang G. J Biol Chem. 2014 Oct 31;289(44):30625-34. doi: 10.1074/jbc.M114.571984. Epub 2014 Sep 4. J Biol Chem. 2014. PMID: 25190803 Free PMC article.
CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G(1) phase to initiate a new cell cycle in HeLa cells.
Chen H, Xu X, Wang G, Zhang B, Wang G, Xin G, Liu J, Jiang Q, Zhang H, Zhang C. Chen H, et al. Among authors: Wang G, Wang G. J Biol Chem. 2017 Jun 16;292(24):10131-10141. doi: 10.1074/jbc.M116.773226. Epub 2017 Apr 26. J Biol Chem. 2017. PMID: 28446612 Free PMC article.
CDK4 protein reaccumulates in the following G(1) phase and shuttles between the nucleus and the cytoplasm to facilitate the nuclear import of cyclin D1. ...RNAi knockdown of CDK4 also induces cytoplasmic retention of cyclin D1 and G(0)/G(1) phase arrest of the cells. Collectively, our data demonstrate that CDK4 protein is degraded in late mitosis and reaccumulates in the following G(1) phase to facilitate the nuclear import of cyclin D1 for activation of CKD4 to initiate a new cell cycle in HeLa cells....
CDK4 protein reaccumulates in the following G(1) phase and shuttles between the nucleus and the cytoplasm to facilitate the nuclear i …
DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Zhang B, Wang G, Xu X, Yang S, Zhuang T, Wang G, Ren H, Cheng SY, Jiang Q, Zhang C. Zhang B, et al. Among authors: Wang G, Wang G. J Biol Chem. 2017 Jan 27;292(4):1351-1360. doi: 10.1074/jbc.M116.765438. Epub 2016 Dec 15. J Biol Chem. 2017. PMID: 27979967 Free PMC article.
Here we demonstrate that the centrosome protein Dzip1 mediates the assembly of the BBSome-Dzip1-PCM1 complex in the centriolar satellites (CS) at the G(0) phase for ciliary translocation of the BBSome. Phosphorylation of Dzip1 at Ser-210 by Plk1 (polo-like kinase 1) during the G(2) phase promotes disassembly of this complex, resulting in removal of Dzip1 and the BBSome from the CS. ...
Here we demonstrate that the centrosome protein Dzip1 mediates the assembly of the BBSome-Dzip1-PCM1 complex in the centriolar satellites (C …
Sp1-dependent activation of HDAC7 is required for platelet-derived growth factor-BB-induced smooth muscle cell differentiation from stem cells.
Zhang L, Jin M, Margariti A, Wang G, Luo Z, Zampetaki A, Zeng L, Ye S, Zhu J, Xiao Q. Zhang L, et al. Among authors: Wang G. J Biol Chem. 2010 Dec 3;285(49):38463-72. doi: 10.1074/jbc.M110.153999. Epub 2010 Oct 1. J Biol Chem. 2010. PMID: 20889501 Free PMC article.
XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling.
Zeng L, Li Y, Yang J, Wang G, Margariti A, Xiao Q, Zampetaki A, Yin X, Mayr M, Mori K, Wang W, Hu Y, Xu Q. Zeng L, et al. Among authors: Wang G, Wang W. Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2134-44. doi: 10.1161/ATVBAHA.115.305420. Epub 2015 Aug 27. Arterioscler Thromb Vasc Biol. 2015. PMID: 26315405
Splicing of histone deacetylase 7 modulates smooth muscle cell proliferation and neointima formation through nuclear β-catenin translocation.
Zhou B, Margariti A, Zeng L, Habi O, Xiao Q, Martin D, Wang G, Hu Y, Wang X, Xu Q. Zhou B, et al. Among authors: Wang G, Wang X. Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2676-84. doi: 10.1161/ATVBAHA.111.230888. Arterioscler Thromb Vasc Biol. 2011. PMID: 21836063
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