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The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers.
Parato KA, Breitbach CJ, Le Boeuf F, Wang J, Storbeck C, Ilkow C, Diallo JS, Falls T, Burns J, Garcia V, Kanji F, Evgin L, Hu K, Paradis F, Knowles S, Hwang TH, Vanderhyden BC, Auer R, Kirn DH, Bell JC. Parato KA, et al. Among authors: wang j. Mol Ther. 2012 Apr;20(4):749-58. doi: 10.1038/mt.2011.276. Epub 2011 Dec 20. Mol Ther. 2012. PMID: 22186794 Free PMC article.
Oncolytic vaccinia virotherapy for endometrial cancer.
Liu YP, Wang J, Avanzato VA, Bakkum-Gamez JN, Russell SJ, Bell JC, Peng KW. Liu YP, et al. Among authors: wang j. Gynecol Oncol. 2014 Mar;132(3):722-9. doi: 10.1016/j.ygyno.2014.01.009. Epub 2014 Jan 14. Gynecol Oncol. 2014. PMID: 24434058 Free PMC article.
Maraba MG1 virus enhances natural killer cell function via conventional dendritic cells to reduce postoperative metastatic disease.
Zhang J, Tai LH, Ilkow CS, Alkayyal AA, Ananth AA, de Souza CT, Wang J, Sahi S, Ly L, Lefebvre C, Falls TJ, Stephenson KB, Mahmoud AB, Makrigiannis AP, Lichty BD, Bell JC, Stojdl DF, Auer RC. Zhang J, et al. Among authors: wang j. Mol Ther. 2014 Jul;22(7):1320-1332. doi: 10.1038/mt.2014.60. Epub 2014 Apr 3. Mol Ther. 2014. PMID: 24695102 Free PMC article.
Rapid Generation of Multiple Loci-Engineered Marker-free Poxvirus and Characterization of a Clinical-Grade Oncolytic Vaccinia Virus.
Guo ZS, Liu Z, Sathaiah M, Wang J, Ravindranathan R, Kim E, Huang S, Kenniston TW, Bell JC, Zeh HJ 3rd, Butterfield LH, Gambotto A, Bartlett DL. Guo ZS, et al. Among authors: wang j. Mol Ther Methods Clin Dev. 2017 Sep 30;7:112-122. doi: 10.1016/j.omtm.2017.09.007. eCollection 2017 Dec 15. Mol Ther Methods Clin Dev. 2017. PMID: 29085848 Free PMC article.
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