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High throughput screening technologies for ion channels.
Yu HB, Li M, Wang WP, Wang XL. Yu HB, et al. Among authors: wang wp, wang xl. Acta Pharmacol Sin. 2016 Jan;37(1):34-43. doi: 10.1038/aps.2015.108. Epub 2015 Dec 14. Acta Pharmacol Sin. 2016. PMID: 26657056 Free PMC article. Review.
Lig4-4 selectively inhibits TREK-1 and plays potent neuroprotective roles in vitro and in rat MCAO model.
Wang W, Liu D, Xiao Q, Cai J, Feng N, Xu S, Wang L, Yin D, Wang X. Wang W, et al. Among authors: wang l, wang x. Neurosci Lett. 2018 Apr 3;671:93-98. doi: 10.1016/j.neulet.2018.02.015. Epub 2018 Feb 10. Neurosci Lett. 2018. PMID: 29438799
An increased TREK-1-like potassium current in ventricular myocytes during rat cardiac hypertrophy.
Wang W, Zhang M, Li P, Yuan H, Feng N, Peng Y, Wang L, Wang X. Wang W, et al. Among authors: wang l, wang x. J Cardiovasc Pharmacol. 2013 Apr;61(4):302-10. doi: 10.1097/FJC.0b013e318280c5a9. J Cardiovasc Pharmacol. 2013. PMID: 23232841
Potassium 2-(1-hydroxypentyl)-benzoate improves depressive-like behaviors in rat model.
Ma H, Wang W, Xu S, Wang L, Wang X. Ma H, et al. Among authors: wang w, wang l, wang x. Acta Pharm Sin B. 2018 Oct;8(6):881-888. doi: 10.1016/j.apsb.2018.08.004. Epub 2018 Aug 20. Acta Pharm Sin B. 2018. PMID: 30505657 Free PMC article.
Parishin C's prevention of Aβ 1-42-induced inhibition of long-term potentiation is related to NMDA receptors.
Liu Z, Wang W, Feng N, Wang L, Shi J, Wang X. Liu Z, et al. Among authors: wang w, wang l, wang x. Acta Pharm Sin B. 2016 May;6(3):189-97. doi: 10.1016/j.apsb.2016.03.009. Epub 2016 Apr 22. Acta Pharm Sin B. 2016. PMID: 27175329 Free PMC article.
Effects of fluoxetine on protein expression of potassium ion channels in the brain of chronic mild stress rats.
Chen C, Wang L, Rong X, Wang W, Wang X. Chen C, et al. Among authors: wang l, wang w, wang x. Acta Pharm Sin B. 2015 Jan;5(1):55-61. doi: 10.1016/j.apsb.2014.12.004. Epub 2014 Dec 30. Acta Pharm Sin B. 2015. PMID: 26579425 Free PMC article.
Electrophysiology and pharmacology of tandem domain potassium channel TREK-1 related BDNF synthesis in rat astrocytes.
Lu L, Wang W, Peng Y, Li J, Wang L, Wang X. Lu L, et al. Among authors: wang w, wang l, wang x. Naunyn Schmiedebergs Arch Pharmacol. 2014 Apr;387(4):303-12. doi: 10.1007/s00210-013-0952-2. Epub 2014 Jan 9. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 24402080
Functional study of TREK-1 potassium channels during rat heart development and cardiac ischemia using RNAi techniques.
Yang X, Guo P, Li J, Wang W, Xu S, Wang L, Wang X. Yang X, et al. Among authors: wang w, wang l, wang x. J Cardiovasc Pharmacol. 2014 Aug;64(2):142-50. doi: 10.1097/FJC.0000000000000099. J Cardiovasc Pharmacol. 2014. PMID: 24705172
Donepezil attenuated oxygen-glucose deprivation insult by blocking Kv2.1 potassium channels.
Yuan H, Wang WP, Feng N, Wang L, Wang XL. Yuan H, et al. Among authors: wang wp, wang l, wang xl. Eur J Pharmacol. 2011 Apr 25;657(1-3):76-83. doi: 10.1016/j.ejphar.2011.01.054. Epub 2011 Feb 11. Eur J Pharmacol. 2011. PMID: 21300054
Over-expressed human TREK-1 inhibits CHO cell proliferation via inhibiting PKA and p38 MAPK pathways and subsequently inducing G1 arrest.
Zhang M, Yin HJ, Wang WP, Li J, Wang XL. Zhang M, et al. Among authors: wang wp, wang xl. Acta Pharmacol Sin. 2016 Sep;37(9):1190-8. doi: 10.1038/aps.2016.65. Epub 2016 Jul 11. Acta Pharmacol Sin. 2016. PMID: 27397543 Free PMC article.
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