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A single nucleotide polymorphism in the matrix metalloproteinase 9 gene (-8202A/G) is associated with thoracic aortic aneurysms and thoracic aortic dissection.
Chen L, Wang X, Carter SA, Shen YH, Bartsch HR, Thompson RW, Coselli JS, Wilcken DL, Wang XL, LeMaire SA. Chen L, et al. Among authors: wang x, wang xl. J Thorac Cardiovasc Surg. 2006 May;131(5):1045-52. doi: 10.1016/j.jtcvs.2006.01.003. J Thorac Cardiovasc Surg. 2006. PMID: 16678588 Free PMC article.
AKT2 confers protection against aortic aneurysms and dissections.
Shen YH, Zhang L, Ren P, Nguyen MT, Zou S, Wu D, Wang XL, Coselli JS, LeMaire SA. Shen YH, et al. Circ Res. 2013 Feb 15;112(4):618-32. doi: 10.1161/CIRCRESAHA.112.300735. Epub 2012 Dec 18. Circ Res. 2013. PMID: 23250987 Free PMC article.
Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells.
Shen YH, Zhang L, Gan Y, Wang X, Wang J, LeMaire SA, Coselli JS, Wang XL. Shen YH, et al. Among authors: wang x, wang j, wang xl. J Biol Chem. 2006 Mar 24;281(12):7727-36. doi: 10.1074/jbc.M511105200. Epub 2006 Jan 17. J Biol Chem. 2006. PMID: 16418168 Free article.
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