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Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice.
Wang X, Inoue S, Gu J, Miyoshi E, Noda K, Li W, Mizuno-Horikawa Y, Nakano M, Asahi M, Takahashi M, Uozumi N, Ihara S, Lee SH, Ikeda Y, Yamaguchi Y, Aze Y, Tomiyama Y, Fujii J, Suzuki K, Kondo A, Shapiro SD, Lopez-Otin C, Kuwaki T, Okabe M, Honke K, Taniguchi N. Wang X, et al. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15791-6. doi: 10.1073/pnas.0507375102. Epub 2005 Oct 18. Proc Natl Acad Sci U S A. 2005. PMID: 16236725 Free PMC article.
Loss of core fucosylation of low-density lipoprotein receptor-related protein-1 impairs its function, leading to the upregulation of serum levels of insulin-like growth factor-binding protein 3 in Fut8-/- mice.
Lee SH, Takahashi M, Honke K, Miyoshi E, Osumi D, Sakiyama H, Ekuni A, Wang X, Inoue S, Gu J, Kadomatsu K, Taniguchi N. Lee SH, et al. Among authors: wang x. J Biochem. 2006 Mar;139(3):391-8. doi: 10.1093/jb/mvj039. J Biochem. 2006. PMID: 16567404
Down-regulation of trypsinogen expression is associated with growth retardation in alpha1,6-fucosyltransferase-deficient mice: attenuation of proteinase-activated receptor 2 activity.
Li W, Nakagawa T, Koyama N, Wang X, Jin J, Mizuno-Horikawa Y, Gu J, Miyoshi E, Kato I, Honke K, Taniguchi N, Kondo A. Li W, et al. Among authors: wang x. Glycobiology. 2006 Oct;16(10):1007-19. doi: 10.1093/glycob/cwl023. Epub 2006 Jul 21. Glycobiology. 2006. PMID: 16861703
Crystal structure of mammalian alpha1,6-fucosyltransferase, FUT8.
Ihara H, Ikeda Y, Toma S, Wang X, Suzuki T, Gu J, Miyoshi E, Tsukihara T, Honke K, Matsumoto A, Nakagawa A, Taniguchi N. Ihara H, et al. Among authors: wang x. Glycobiology. 2007 May;17(5):455-66. doi: 10.1093/glycob/cwl079. Epub 2006 Dec 15. Glycobiology. 2007. PMID: 17172260
From glycomics to functional glycomics of sugar chains: Identification of target proteins with functional changes using gene targeting mice and knock down cells of FUT8 as examples.
Kondo A, Li W, Nakagawa T, Nakano M, Koyama N, Wang X, Gu J, Miyoshi E, Taniguchi N. Kondo A, et al. Among authors: wang x. Biochim Biophys Acta. 2006 Dec;1764(12):1881-9. doi: 10.1016/j.bbapap.2006.10.011. Epub 2006 Nov 10. Biochim Biophys Acta. 2006. PMID: 17174880 Review.
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