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Visualizing the mechanical activation of Src.
Wang Y, Botvinick EL, Zhao Y, Berns MW, Usami S, Tsien RY, Chien S. Wang Y, et al. Nature. 2005 Apr 21;434(7036):1040-5. doi: 10.1038/nature03469. Nature. 2005. PMID: 15846350
Shear Stress Regulates the Flk-1/Cbl/PI3K/NF-κB Pathway Via Actin and Tyrosine Kinases.
Wang Y, Flores L, Lu S, Miao H, Li YS, Chien S. Wang Y, et al. Cell Mol Bioeng. 2009 Sep 1;2(3):341-350. doi: 10.1007/s12195-009-0069-3. Cell Mol Bioeng. 2009. PMID: 20011623 Free PMC article.
The shear-activated integrins can also transactivate Flk-1 (a receptor for vascular endothelial growth factor (VEGF)) [Wang, Y., H. Miao, S. Li, K. D. Chen, Y. S. Li, et al. Am. J. Physiol. Cell Physiol. 283:C1540-C1547, 2002], which subsequently recruits Cas …
The shear-activated integrins can also transactivate Flk-1 (a receptor for vascular endothelial growth factor (VEGF)) [Wang, Y
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