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Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.
Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Takeda K, Utsunomiya H, Oda K, Warabi E, Ishii T, Osaka K, Hyodo I, Yamamoto M. Okada K, et al. Among authors: warabi e. Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G735-47. doi: 10.1152/ajpgi.90321.2008. Epub 2008 Aug 7. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18687751 Free article.
Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems.
Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Sugimoto H, Utsunomiya H, Oda K, Warabi E, Ishii T, Yamamoto M. Okada K, et al. Among authors: warabi e. Biochem Biophys Res Commun. 2009 Nov 20;389(3):431-6. doi: 10.1016/j.bbrc.2009.08.156. Epub 2009 Sep 2. Biochem Biophys Res Commun. 2009. PMID: 19732748
Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.
Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M. Sugimoto H, et al. Among authors: warabi e. Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G283-94. doi: 10.1152/ajpgi.00296.2009. Epub 2009 Nov 19. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 19926817 Free article.
Amelioration of cisplatin-induced nephrotoxicity in peroxiredoxin I-deficient mice.
Okada K, Ma D, Warabi E, Morito N, Akiyama K, Murata Y, Yamagata K, Bukawa H, Shoda J, Ishii T, Yanagawa T. Okada K, et al. Among authors: warabi e. Cancer Chemother Pharmacol. 2013 Feb;71(2):503-9. doi: 10.1007/s00280-012-2046-0. Epub 2012 Dec 11. Cancer Chemother Pharmacol. 2013. PMID: 23228991
Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain.
Harada H, Warabi E, Matsuki T, Yanagawa T, Okada K, Uwayama J, Ikeda A, Nakaso K, Kirii K, Noguchi N, Bukawa H, Siow RC, Mann GE, Shoda J, Ishii T, Sakurai T. Harada H, et al. Among authors: warabi e. J Neurosci. 2013 Sep 11;33(37):14767-77. doi: 10.1523/JNEUROSCI.2954-12.2013. J Neurosci. 2013. PMID: 24027277 Free PMC article.
80 results