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YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology.
Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, Saito T, Ichise A, Shibata S, Arai H, Saido T, Sudol M, Muramatsu SI, Okano H, Mufson EJ, Sobue G, Murayama S, Okazawa H. Tanaka H, et al. Among authors: waragai m. Nat Commun. 2020 Jan 24;11(1):507. doi: 10.1038/s41467-020-14353-6. Nat Commun. 2020. PMID: 31980612 Free PMC article.
DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Homma H, Tanaka H, Jin M, Jin X, Huang Y, Yoshioka Y, Bertens CJ, Tsumaki K, Kondo K, Shiwaku H, Tagawa K, Akatsu H, Atsuta N, Katsuno M, Furukawa K, Ishiki A, Waragai M, Ohtomo G, Iwata A, Yokota T, Inoue H, Arai H, Sobue G, Sone M, Fujita K, Okazawa H. Homma H, et al. Among authors: waragai m. Life Sci Alliance. 2021 Jun 15;4(7):e202101022. doi: 10.26508/lsa.202101022. Print 2021 Jul. Life Sci Alliance. 2021. PMID: 34130995 Free PMC article.
[Pathobiology of Alzheimer's disease and biomarker development].
Arai H, Okamura N, Waragai M, Furukawa K, Yanai K, Kudo Y. Arai H, et al. Among authors: waragai m. Nihon Yakurigaku Zasshi. 2010 Jan;135(1):3-7. doi: 10.1254/fpj.135.3. Nihon Yakurigaku Zasshi. 2010. PMID: 20075563 Review. Japanese. No abstract available.
Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.
Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I. Okazawa H, et al. Among authors: waragai m. Neuron. 2002 May 30;34(5):701-13. doi: 10.1016/s0896-6273(02)00697-9. Neuron. 2002. PMID: 12062018 Free article.
Presenilin 1 binds to amyloid precursor protein directly.
Waragai M, Imafuku I, Takeuchi S, Kanazawa I, Oyama F, Udagawa Y, Kawabata M, Okazawa H. Waragai M, et al. Biochem Biophys Res Commun. 1997 Oct 20;239(2):480-2. doi: 10.1006/bbrc.1997.7488. Biochem Biophys Res Commun. 1997. PMID: 9344855
Polar amino acid-rich sequences bind to polyglutamine tracts.
Imafuku I, Waragai M, Takeuchi S, Kanazawa I, Kawabata M, Mouradian MM, Okazawa H. Imafuku I, et al. Among authors: waragai m. Biochem Biophys Res Commun. 1998 Dec 9;253(1):16-20. doi: 10.1006/bbrc.1998.9725. Biochem Biophys Res Commun. 1998. PMID: 9875212
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