Ward I - Search Results

1

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A. Fernandez-Capetillo O, et al. Among authors: ward i. Nat Cell Biol. 2002 Dec;4(12):993-7. doi: 10.1038/ncb884. Nat Cell Biol. 2002. PMID: 12447390

2

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.

Sengupta S, Robles AI, Linke SP, Sinogeeva NI, Zhang R, Pedeux R, Ward IM, Celeste A, Nussenzweig A, Chen J, Halazonetis TD, Harris CC. Sengupta S, et al. Among authors: ward im. J Cell Biol. 2004 Sep 13;166(6):801-13. doi: 10.1083/jcb.200405128. J Cell Biol. 2004. PMID: 15364958 Free PMC article.

3

53BP1 is required for class switch recombination.

Ward IM, Reina-San-Martin B, Olaru A, Minn K, Tamada K, Lau JS, Cascalho M, Chen L, Nussenzweig A, Livak F, Nussenzweig MC, Chen J. Ward IM, et al. J Cell Biol. 2004 May 24;165(4):459-64. doi: 10.1083/jcb.200403021. J Cell Biol. 2004. PMID: 15159415 Free PMC article.

4

Early events in the DNA damage response.

Ward I, Chen J. Ward I, et al. Curr Top Dev Biol. 2004;63:1-35. doi: 10.1016/S0070-2153(04)63001-8. Curr Top Dev Biol. 2004. PMID: 15536012 Review.

5

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.

Minter-Dykhouse K, Ward I, Huen MS, Chen J, Lou Z. Minter-Dykhouse K, et al. Among authors: ward i. J Cell Biol. 2008 Jun 2;181(5):727-35. doi: 10.1083/jcb.200801083. Epub 2008 May 26. J Cell Biol. 2008. PMID: 18504301 Free PMC article.

6

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress.

Ward IM, Chen J. Ward IM, et al. J Biol Chem. 2001 Dec 21;276(51):47759-62. doi: 10.1074/jbc.C100569200. Epub 2001 Oct 22. J Biol Chem. 2001. PMID: 11673449 Free article.

7

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.

Ward IM, Minn K, van Deursen J, Chen J. Ward IM, et al. Mol Cell Biol. 2003 Apr;23(7):2556-63. doi: 10.1128/MCB.23.7.2556-2563.2003. Mol Cell Biol. 2003. PMID: 12640136 Free PMC article.

8

Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX.

Ward IM, Minn K, Jorda KG, Chen J. Ward IM, et al. J Biol Chem. 2003 May 30;278(22):19579-82. doi: 10.1074/jbc.C300117200. Epub 2003 Apr 15. J Biol Chem. 2003. PMID: 12697768 Free article.

9

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.

Botuyan MV, Lee J, Ward IM, Kim JE, Thompson JR, Chen J, Mer G. Botuyan MV, et al. Cell. 2006 Dec 29;127(7):1361-73. doi: 10.1016/j.cell.2006.10.043. Cell. 2006. PMID: 17190600 Free PMC article.

10

53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice.

Ward IM, Difilippantonio S, Minn K, Mueller MD, Molina JR, Yu X, Frisk CS, Ried T, Nussenzweig A, Chen J. Ward IM, et al. Mol Cell Biol. 2005 Nov;25(22):10079-86. doi: 10.1128/MCB.25.22.10079-10086.2005. Mol Cell Biol. 2005. PMID: 16260621 Free PMC article.

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