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Page 1
Repeated blood-brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 trial.
Sonabend AM, Gould A, Amidei C, Ward R, Schmidt KA, Zhang DY, Gomez C, Bebawy JF, Liu BP, Bouchoux G, Desseaux C, Helenowski IB, Lukas RV, Dixit K, Kumthekar P, Arrieta VA, Lesniak MS, Carpentier A, Zhang H, Muzzio M, Canney M, Stupp R. Sonabend AM, et al. Among authors: ward r. Lancet Oncol. 2023 May;24(5):509-522. doi: 10.1016/S1470-2045(23)00112-2. Lancet Oncol. 2023. PMID: 37142373 Free PMC article. Clinical Trial.
Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas.
Arrieta VA, Gould A, Kim KS, Habashy KJ, Dmello C, Vázquez-Cervantes GI, Palacín-Aliana I, McManus G, Amidei C, Gomez C, Dhiantravan S, Chen L, Zhang DY, Saganty R, Cholak ME, Pandey S, McCord M, McCortney K, Castro B, Ward R, Muzzio M, Bouchoux G, Desseaux C, Canney M, Carpentier A, Zhang B, Miska JM, Lesniak MS, Horbinski CM, Lukas RV, Stupp R, Lee-Chang C, Sonabend AM. Arrieta VA, et al. Among authors: ward r. Nat Commun. 2024 Jun 6;15(1):4698. doi: 10.1038/s41467-024-48326-w. Nat Commun. 2024. PMID: 38844770 Free PMC article.
Endothelial response to blood-brain barrier disruption in the human brain.
Gould A, Luan Y, Hou Y, Korobova FV, Chen L, Arrieta VA, Amidei C, Ward R, Gomez C, Castro B, Habashy K, Zhang D, Youngblood M, Dmello C, Bebawy J, Bouchoux G, Stupp R, Canney M, Yue F, Iruela-Arispe ML, Sonabend AM. Gould A, et al. Among authors: ward r. JCI Insight. 2024 Dec 26;10(4):e187328. doi: 10.1172/jci.insight.187328. JCI Insight. 2024. PMID: 39724015 Free PMC article. Clinical Trial.
Pharmacokinetic analysis of carboplatin and fluorescein brain permanence following ultrasound-based blood-brain barrier opening.
Habashy KJ, Synold TW, Feng Y, Gomez C, Amidei C, Ward R, VanderMolen S, Zarrieneh A, Kim KS, Arrieta VA, Fares J, Burdett KB, Zhang H, Dmello C, Chen L, Bebawy JF, Canney M, Stupp R, Badie B, Portnow J, Sonabend AM. Habashy KJ, et al. Among authors: ward r. medRxiv [Preprint]. 2025 Jan 20:2025.01.20.25320847. doi: 10.1101/2025.01.20.25320847. medRxiv. 2025. Update in: Clin Cancer Res. 2025 Aug 14;31(16):3562-3570. doi: 10.1158/1078-0432.CCR-25-0080. PMID: 39974025 Free PMC article. Updated. Preprint.
Pharmacokinetic Analysis of Carboplatin and Fluorescein Brain Retention following Ultrasound-Based Blood-Brain Barrier Opening.
Habashy KJ, Synold TW, Feng Y, Gomez C, Amidei C, Ward R, VanderMolen S, Zarrieneh A, Kim KS, Gomez M, Arrieta VA, Fares J, Burdett KB, Zhang H, Dmello C, Chen L, Bebawy JF, Canney M, Stupp R, Badie B, Portnow J, Sonabend AM. Habashy KJ, et al. Among authors: ward r. Clin Cancer Res. 2025 Aug 14;31(16):3562-3570. doi: 10.1158/1078-0432.CCR-25-0080. Clin Cancer Res. 2025. PMID: 40495421 Free PMC article. Clinical Trial.
Dynamic release of extracellular particles after opening of the blood-brain barrier predicts glioblastoma susceptibility to paclitaxel.
Youngblood MW, Kumari A, Kang YT, Gould A, Habashy K, Gomez M, Lingamarla H, Morey T, Chen L, Congivaram H, Ward R, Zhang H, Sears TK, McCortney K, Pituch KC, Torres Ponce EM, Zarrieneh A, Nieves M, Vandermolen S, Primdahl D, Dixit K, Lukas RV, Kumthekar P, Dmello C, Bouchoux G, Canney M, Amidei C, Stupp R, Nagrath S, Sonabend AM. Youngblood MW, et al. Among authors: ward r. Nat Commun. 2025 Dec 16;16(1):11045. doi: 10.1038/s41467-025-65681-4. Nat Commun. 2025. PMID: 41402297 Free PMC article. Clinical Trial.
Spatial biomarker discovery via interpretable semantic learning in histopathology.
Liang J, Jiang X, Reitsam NG, Lenz T, Zhang L, Gustav M, Carrero ZI, Muti HS, Neidlinger P, Clusmann J, Žigutytė L, Sainath V, Wolf F, Boardman LA, French AJ, Goode EL, Gsur A, Brezina S, Gunter MJ, Steinfelder R, Harrison T, Peters U, Phipps AI, Quirke P, West NP, Hoffmeister M, Brenner H, Wankhede D, Jonnagaddala J, Hawkins N, Ward RL, Fountzilas E, Papadopoulou K, Fountzilas G, André T, Taieb J, Emile JF, Svrcek M, Kong L, Kather JN. Liang J, et al. Among authors: ward rl. Cancer Cell. 2026 Jun 11:S1535-6108(26)00259-X. doi: 10.1016/j.ccell.2026.05.014. Online ahead of print. Cancer Cell. 2026. PMID: 42276049
4,672 results