Evidence for the role of a peroxidase compound I-type intermediate in the oxidation of glutathione, NADH, ascorbate, and dichlorofluorescin by cytochrome c/H2O2. Implications for oxidative stress during apoptosis.
Lawrence A, Jones CM, Wardman P, Burkitt MJ.
Lawrence A, et al. Among authors: wardman p.
J Biol Chem. 2003 Aug 8;278(32):29410-9. doi: 10.1074/jbc.M300054200. Epub 2003 May 14.
J Biol Chem. 2003.
PMID: 12748170
Recently, we showed that cytochrome c is a potent catalyst of 2',7'-dichlorofluorescin oxidation to the fluorescent 2',7'-dichlorofluorescein by these species, leading to the conclusion that 2',7'-dichlorofluorescein fluorescence is a reflection of cytosolic cytochrome c concentr …
Recently, we showed that cytochrome c is a potent catalyst of 2',7'-dichlorofluorescin oxidation to the fluorescent 2',7'-dichlorofluorescei …