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Catalytic antibodies in arrhythmogenic cardiomyopathy patients cleave desmoglein 2 and N-cadherin and impair cardiomyocyte cohesion.
Yeruva S, Stangner K, Jungwirth A, Hiermaier M, Shoykhet M, Kugelmann D, Hertl M, Egami S, Ishii N, Koga H, Hashimoto T, Weis M, Beckmann BM, Biller R, Schüttler D, Kääb S, Waschke J. Yeruva S, et al. Among authors: waschke j. Cell Mol Life Sci. 2023 Jul 14;80(8):203. doi: 10.1007/s00018-023-04853-1. Cell Mol Life Sci. 2023. PMID: 37450050 Free PMC article.
Adducin is required for desmosomal cohesion in keratinocytes.
Rötzer V, Breit A, Waschke J, Spindler V. Rötzer V, et al. Among authors: waschke j. J Biol Chem. 2014 May 23;289(21):14925-40. doi: 10.1074/jbc.M113.527127. Epub 2014 Apr 7. J Biol Chem. 2014. PMID: 24711455 Free PMC article.
Desmoglein-2 interaction is crucial for cardiomyocyte cohesion and function.
Schlipp A, Schinner C, Spindler V, Vielmuth F, Gehmlich K, Syrris P, Mckenna WJ, Dendorfer A, Hartlieb E, Waschke J. Schlipp A, et al. Among authors: waschke j. Cardiovasc Res. 2014 Nov 1;104(2):245-57. doi: 10.1093/cvr/cvu206. Epub 2014 Sep 11. Cardiovasc Res. 2014. PMID: 25213555
Adducin is involved in endothelial barrier stabilization.
Kugelmann D, Waschke J, Radeva MY. Kugelmann D, et al. Among authors: waschke j. PLoS One. 2015 May 15;10(5):e0126213. doi: 10.1371/journal.pone.0126213. eCollection 2015. PLoS One. 2015. PMID: 25978380 Free PMC article.
209 results