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Candidate gene for the chromosome 1 familial Alzheimer's disease locus.
Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu CE, Jondro PD, Schmidt SD, Wang K, et al. Levy-Lahad E, et al. Among authors: Wasco W. Science. 1995 Aug 18;269(5226):973-7. doi: 10.1126/science.7638622. Science. 1995. PMID: 7638622
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HA, Haines JL, Perkicak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St George-Hyslop PH. Sherrington R, et al. Among authors: Wasco W. Nature. 1995 Jun 29;375(6534):754-60. doi: 10.1038/375754a0. Nature. 1995. PMID: 7596406
Search for the genes responsible for familial Alzheimer's disease.
Wasco W, Peppercorn J, Tanzi RE. Wasco W, et al. Ann N Y Acad Sci. 1993 Sep 24;695:203-8. doi: 10.1111/j.1749-6632.1993.tb23053.x. Ann N Y Acad Sci. 1993. PMID: 8239284 Review.
Genetic heterogeneity of gene defects responsible for familial Alzheimer disease.
Tanzi R, Gaston S, Bush A, Romano D, Pettingell W, Peppercorn J, Paradis M, Gurubhagavatula S, Jenkins B, Wasco W. Tanzi R, et al. Among authors: Wasco W. Genetica. 1993;91(1-3):255-63. doi: 10.1007/bf01436002. Genetica. 1993. PMID: 8125274 Review.
Familial Alzheimer's chromosome 14 mutations.
Wasco W, Pettingell WP, Jondro PD, Schmidt SD, Gurubhagavatula S, Rodes L, DiBlasi T, Romano DM, Guenette SY, Kovacs DM, et al. Wasco W, et al. Nat Med. 1995 Sep;1(9):848. doi: 10.1038/nm0995-848a. Nat Med. 1995. PMID: 7585193 No abstract available.
The gene defects responsible for familial Alzheimer's disease.
Tanzi RE, Kovacs DM, Kim TW, Moir RD, Guenette SY, Wasco W. Tanzi RE, et al. Among authors: Wasco W. Neurobiol Dis. 1996;3(3):159-68. doi: 10.1006/nbdi.1996.0016. Neurobiol Dis. 1996. PMID: 8980016 Review.
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease.
Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, Bird TD, Hardy J, Hutton M, Kukull W, Larson E, Levy-Lahad E, Viitanen M, Peskind E, Poorkaj P, Schellenberg G, Tanzi R, Wasco W, Lannfelt L, Selkoe D, Younkin S. Scheuner D, et al. Among authors: Wasco W. Nat Med. 1996 Aug;2(8):864-70. doi: 10.1038/nm0896-864. Nat Med. 1996. PMID: 8705854
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