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13,189 results
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ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA.
Fujishiro SH, Tanimura S, Mure S, Kashimoto Y, Watanabe K, Kohno M. Fujishiro SH, et al. Among authors: watanabe k. Biochem Biophys Res Commun. 2008 Mar 28;368(1):162-7. doi: 10.1016/j.bbrc.2008.01.066. Epub 2008 Jan 22. Biochem Biophys Res Commun. 2008. PMID: 18211802
Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models.
Sakamoto T, Ozaki K, Fujio K, Kajikawa SH, Uesato S, Watanabe K, Tanimura S, Koji T, Kohno M. Sakamoto T, et al. Among authors: watanabe k. Biochem Biophys Res Commun. 2013 Apr 19;433(4):456-62. doi: 10.1016/j.bbrc.2013.03.009. Epub 2013 Mar 15. Biochem Biophys Res Commun. 2013. PMID: 23501104
SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation.
Tanimura S, Hashizume J, Kurosaki Y, Sei K, Gotoh A, Ohtake R, Kawano M, Watanabe K, Kohno M. Tanimura S, et al. Among authors: watanabe k. Genes Cells. 2011 May;16(5):514-26. doi: 10.1111/j.1365-2443.2011.01503.x. Epub 2011 Apr 18. Genes Cells. 2011. PMID: 21501342
Blockade of the extracellular signal-regulated kinase pathway enhances the therapeutic efficacy of microtubule-destabilizing agents in human tumor xenograft models.
Watanabe K, Tanimura S, Uchiyama A, Sakamoto T, Kawabata T, Ozaki K, Kohno M. Watanabe K, et al. Clin Cancer Res. 2010 Feb 15;16(4):1170-8. doi: 10.1158/1078-0432.CCR-09-2482. Epub 2010 Feb 9. Clin Cancer Res. 2010. PMID: 20145173
Blockade of the phosphatidylinositol-3-kinase-Akt signaling pathway enhances the induction of apoptosis by microtubule-destabilizing agents in tumor cells in which the pathway is constitutively activated.
Fujiwara Y, Hosokawa Y, Watanabe K, Tanimura S, Ozaki K, Kohno M. Fujiwara Y, et al. Among authors: watanabe k. Mol Cancer Ther. 2007 Mar;6(3):1133-42. doi: 10.1158/1535-7163.MCT-06-0639. Mol Cancer Ther. 2007. PMID: 17363506
ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips.
Tanimura S, Hashizume J, Arichika N, Watanabe K, Ohyama K, Takeda K, Kohno M. Tanimura S, et al. Among authors: watanabe k. J Cell Biol. 2016 Aug 15;214(4):475-89. doi: 10.1083/jcb.201503123. Epub 2016 Aug 8. J Cell Biol. 2016. PMID: 27502487 Free PMC article.
Blockade of constitutively activated ERK signaling enhances cytotoxicity of microtubule-destabilizing agents in tumor cells.
Tanimura S, Uchiyama A, Watanabe K, Yasunaga M, Inada Y, Kawabata T, Iwashita K, Noda S, Ozaki K, Kohno M. Tanimura S, et al. Among authors: watanabe k. Biochem Biophys Res Commun. 2009 Jan 16;378(3):650-5. doi: 10.1016/j.bbrc.2008.11.109. Epub 2008 Dec 4. Biochem Biophys Res Commun. 2009. PMID: 19059207
[Application of NGF/PC12 cell system for the screening of tubulin inhibitors].
Kohno M, Watanabe K, Tanimura S. Kohno M, et al. Among authors: watanabe k. Gan To Kagaku Ryoho. 2004 Apr;31(4):501-6. Gan To Kagaku Ryoho. 2004. PMID: 15114690 Japanese.
Immunohistochemical analysis of ubiquilin-1 in the human hippocampus: association with neurofibrillary tangle pathology.
Mizukami K, Abrahamson EE, Mi Z, Ishikawa M, Watanabe K, Kinoshita S, Asada T, Ikonomovic MD. Mizukami K, et al. Among authors: watanabe k. Neuropathology. 2014 Feb;34(1):11-8. doi: 10.1111/neup.12055. Epub 2013 Jul 21. Neuropathology. 2014. PMID: 23869942 Free PMC article.
Cep57 and Cep57L1 maintain centriole engagement in interphase to ensure centriole duplication cycle.
Ito KK, Watanabe K, Ishida H, Matsuhashi K, Chinen T, Hata S, Kitagawa D. Ito KK, et al. Among authors: watanabe k. J Cell Biol. 2021 Mar 1;220(3):e202005153. doi: 10.1083/jcb.202005153. J Cell Biol. 2021. PMID: 33492359
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