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15,147 results

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Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development.
Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A. Marx U, et al. Among authors: watanabe k. ALTEX. 2020;37(3):365-394. doi: 10.14573/altex.2001241. Epub 2020 Feb 28. ALTEX. 2020. PMID: 32113184 Free PMC article.
Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models.
Yamada M, Inoue SI, Sugiyama D, Nishiya Y, Ishizuka T, Watanabe A, Watanabe K, Yamashita S, Watanabe N. Yamada M, et al. Among authors: watanabe k, watanabe n, watanabe a. Drug Metab Dispos. 2020 Apr;48(4):288-296. doi: 10.1124/dmd.119.089599. Epub 2020 Jan 29. Drug Metab Dispos. 2020. PMID: 31996361
Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver.
Ichida H, Fukami T, Amai K, Suzuki K, Mishiro K, Takano S, Obuchi W, Zhang Z, Watanabe A, Nakano M, Watanabe K, Nakajima M. Ichida H, et al. Among authors: watanabe k, watanabe a. Drug Metab Dispos. 2023 Jan;51(1):17-28. doi: 10.1124/dmd.122.001037. Epub 2022 Oct 30. Drug Metab Dispos. 2023. PMID: 36310032
The effectiveness of endoscopic resection for colorectal neoplasms in ulcerative colitis: a multicenter registration study.
Hirai M, Yanai S, Kunisaki R, Nishio M, Watanabe K, Sato T, Ishihara S, Anzai H, Hisabe T, Yasukawa S, Maeda Y, Takishima K, Ohno A, Shiga H, Uraoka T, Itoi Y, Ogata H, Takabayashi K, Yoshida N, Saito Y, Takamaru H, Kawasaki K, Esaki M, Tsuruoka N, Hisamatsu T, Matsumoto T. Hirai M, et al. Among authors: watanabe k. Gastrointest Endosc. 2023 May 30:S0016-5107(23)02606-8. doi: 10.1016/j.gie.2023.05.058. Online ahead of print. Gastrointest Endosc. 2023. PMID: 37263363
Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice.
Kato M, Yamaguchi M, Ooka A, Takahashi R, Suzuki T, Onoda K, Yoshikawa Y, Tsunematsu Y, Sato M, Yoshioka Y, Igarashi M, Hayakawa S, Shoji K, Shoji Y, Ishikawa T, Watanabe K, Miyoshi N. Kato M, et al. Among authors: watanabe k. Sci Rep. 2023 Jun 1;13(1):8924. doi: 10.1038/s41598-023-36091-7. Sci Rep. 2023. PMID: 37264108
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