Watase K - Search Results

1

Regional differences of somatic CAG repeat instability do not account for selective neuronal vulnerability in a knock-in mouse model of SCA1.

Watase K, Venken KJ, Sun Y, Orr HT, Zoghbi HY. Watase K, et al. Hum Mol Genet. 2003 Nov 1;12(21):2789-95. doi: 10.1093/hmg/ddg300. Epub 2003 Sep 2. Hum Mol Genet. 2003. PMID: 12952864

2

The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7.

Gatchel JR, Watase K, Thaller C, Carson JP, Jafar-Nejad P, Shaw C, Zu T, Orr HT, Zoghbi HY. Gatchel JR, et al. Among authors: watase k. Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1291-6. doi: 10.1073/pnas.0711257105. Epub 2008 Jan 23. Proc Natl Acad Sci U S A. 2008. PMID: 18216249 Free PMC article.

3

A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration.

Watase K, Weeber EJ, Xu B, Antalffy B, Yuva-Paylor L, Hashimoto K, Kano M, Atkinson R, Sun Y, Armstrong DL, Sweatt JD, Orr HT, Paylor R, Zoghbi HY. Watase K, et al. Neuron. 2002 Jun 13;34(6):905-19. doi: 10.1016/s0896-6273(02)00733-x. Neuron. 2002. PMID: 12086639

4

Modelling brain diseases in mice: the challenges of design and analysis.

Watase K, Zoghbi HY. Watase K, et al. Nat Rev Genet. 2003 Apr;4(4):296-307. doi: 10.1038/nrg1045. Nat Rev Genet. 2003. PMID: 12671660 Review.

5

Impaired striatal dopamine release in homozygous Vps35 D620N knock-in mice.

Ishizu N, Yui D, Hebisawa A, Aizawa H, Cui W, Fujita Y, Hashimoto K, Ajioka I, Mizusawa H, Yokota T, Watase K. Ishizu N, et al. Among authors: watase k. Hum Mol Genet. 2016 Oct 15;25(20):4507-4517. doi: 10.1093/hmg/ddw279. Hum Mol Genet. 2016. PMID: 28173004

6

Alternative splicing in the C-terminal tail of Cav2.1 is essential for preventing a neurological disease in mice.

Aikawa T, Watanabe T, Miyazaki T, Mikuni T, Wakamori M, Sakurai M, Aizawa H, Ishizu N, Watanabe M, Kano M, Mizusawa H, Watase K. Aikawa T, et al. Among authors: watase k. Hum Mol Genet. 2017 Aug 15;26(16):3094-3104. doi: 10.1093/hmg/ddx193. Hum Mol Genet. 2017. PMID: 28510727

7

RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair.

Taniguchi JB, Kondo K, Fujita K, Chen X, Homma H, Sudo T, Mao Y, Watase K, Tanaka T, Tagawa K, Tamura T, Muramatsu SI, Okazawa H. Taniguchi JB, et al. Among authors: watase k. Hum Mol Genet. 2016 Oct 15;25(20):4432-4447. doi: 10.1093/hmg/ddw272. Hum Mol Genet. 2016. PMID: 28173122

8

Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model.

Aikawa T, Mogushi K, Iijima-Tsutsui K, Ishikawa K, Sakurai M, Tanaka H, Mizusawa H, Watase K. Aikawa T, et al. Among authors: watase k. Hum Mol Genet. 2015 Sep 1;24(17):4780-91. doi: 10.1093/hmg/ddv202. Epub 2015 Jun 1. Hum Mol Genet. 2015. PMID: 26034136 Free PMC article.

9

Repeat instability and motor incoordination in mice with a targeted expanded CAG repeat in the Sca1 locus.

Lorenzetti D, Watase K, Xu B, Matzuk MM, Orr HT, Zoghbi HY. Lorenzetti D, et al. Among authors: watase k. Hum Mol Genet. 2000 Mar 22;9(5):779-85. doi: 10.1093/hmg/9.5.779. Hum Mol Genet. 2000. PMID: 10749985

10

Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10.

Matsuura T, Yamagata T, Burgess DL, Rasmussen A, Grewal RP, Watase K, Khajavi M, McCall AE, Davis CF, Zu L, Achari M, Pulst SM, Alonso E, Noebels JL, Nelson DL, Zoghbi HY, Ashizawa T. Matsuura T, et al. Among authors: watase k. Nat Genet. 2000 Oct;26(2):191-4. doi: 10.1038/79911. Nat Genet. 2000. PMID: 11017075

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