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Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases.
Waterman H, Yarden Y. Waterman H, et al. FEBS Lett. 2001 Feb 16;490(3):142-52. doi: 10.1016/s0014-5793(01)02117-2. FEBS Lett. 2001. PMID: 11223029 Review.
A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling.
Waterman H, Katz M, Rubin C, Shtiegman K, Lavi S, Elson A, Jovin T, Yarden Y. Waterman H, et al. EMBO J. 2002 Feb 1;21(3):303-13. doi: 10.1093/emboj/21.3.303. EMBO J. 2002. PMID: 11823423 Free PMC article.
Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome.
Bao J, Alroy I, Waterman H, Schejter ED, Brodie C, Gruenberg J, Yarden Y. Bao J, et al. Among authors: waterman h. J Biol Chem. 2000 Aug 25;275(34):26178-86. doi: 10.1074/jbc.M002367200. J Biol Chem. 2000. PMID: 10816576
Molecular requirements for the effect of neuregulin on cell spreading, motility and colony organization.
Chausovsky A, Waterman H, Elbaum M, Yarden Y, Geiger B, Bershadsky AD. Chausovsky A, et al. Among authors: waterman h. Oncogene. 2000 Feb 17;19(7):878-88. doi: 10.1038/sj.onc.1203410. Oncogene. 2000. PMID: 10702796
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.
Levkowitz G, Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I, Lavi S, Iwai K, Reiss Y, Ciechanover A, Lipkowitz S, Yarden Y. Levkowitz G, et al. Among authors: waterman h. Mol Cell. 1999 Dec;4(6):1029-40. doi: 10.1016/s1097-2765(00)80231-2. Mol Cell. 1999. PMID: 10635327
The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor.
Waterman H, Levkowitz G, Alroy I, Yarden Y. Waterman H, et al. J Biol Chem. 1999 Aug 6;274(32):22151-4. doi: 10.1074/jbc.274.32.22151. J Biol Chem. 1999. PMID: 10428778
The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.
Waterman H, Alroy I, Strano S, Seger R, Yarden Y. Waterman H, et al. EMBO J. 1999 Jun 15;18(12):3348-58. doi: 10.1093/emboj/18.12.3348. EMBO J. 1999. PMID: 10369675 Free PMC article.
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor.
Levkowitz G, Waterman H, Zamir E, Kam Z, Oved S, Langdon WY, Beguinot L, Geiger B, Yarden Y. Levkowitz G, et al. Among authors: waterman h. Genes Dev. 1998 Dec 1;12(23):3663-74. doi: 10.1101/gad.12.23.3663. Genes Dev. 1998. PMID: 9851973 Free PMC article.
Pathogenic poxviruses reveal viral strategies to exploit the ErbB signaling network.
Tzahar E, Moyer JD, Waterman H, Barbacci EG, Bao J, Levkowitz G, Shelly M, Strano S, Pinkas-Kramarski R, Pierce JH, Andrews GC, Yarden Y. Tzahar E, et al. Among authors: waterman h. EMBO J. 1998 Oct 15;17(20):5948-63. doi: 10.1093/emboj/17.20.5948. EMBO J. 1998. PMID: 9774339 Free PMC article.
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers.
Lenferink AE, Pinkas-Kramarski R, van de Poll ML, van Vugt MJ, Klapper LN, Tzahar E, Waterman H, Sela M, van Zoelen EJ, Yarden Y. Lenferink AE, et al. Among authors: waterman h. EMBO J. 1998 Jun 15;17(12):3385-97. doi: 10.1093/emboj/17.12.3385. EMBO J. 1998. PMID: 9628875 Free PMC article.
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